DL-Dithiothreitol
SIAL/D5545 - BioXtra, ≥99.0% (titration)
Synonym: threo-
CAS Number: 3483-12-3
Empirical Formula (Hill Notation): C4H10O2S2
Molecular Weight: 154.25
EC Number: 222-468-7
MDL Number: MFCD00004877
Linear Formula: HSCH2CH(OH)CH(OH)CH2SH
Product Type: Chemical
| absorption | ≤0.100 at 280 in H2O at 0.1 M |
| ≤0.400 at 260 in H2O at 0.1 M | |
| anion traces | sulfate (SO42-): ≤0.005% |
| assay | ≥99.0% (titration) |
| cation traces | Al: ≤0.0005% |
| As: ≤0.0001% | |
| Ba: ≤0.0005% | |
| Bi: ≤0.0005% | |
| Ca: ≤0.001% | |
| Cd: ≤0.0005% | |
| Co: ≤0.0005% | |
| Cr: ≤0.0005% | |
| Cu: ≤0.0005% | |
| Fe: ≤0.0005% | |
| K: ≤0.005% | |
| Li: ≤0.0005% | |
| Mg: ≤0.0005% | |
| Mn: ≤0.0005% | |
| Mo: ≤0.0005% | |
| Na: ≤0.1% | |
| Ni: ≤0.0005% | |
| Pb: ≤0.0005% | |
| Sr: ≤0.0005% | |
| Zn: ≤0.0005% | |
| form | powder |
| impurities | Insoluble matter, passes filter test |
| ≤0.3% 4,5-dihydroxy-1,2-dithian |
|
| InChI | 1S/C4H10O2S2/c5-3(1-7)4(6 |
| InChI key | VHJLVAABSRFDPM-QWWZWVQMSA |
| mp | 41-44 °C (lit.) |
| pH | 4.0-6.0 (20-25 °C, 0.1 m in H2O) |
| product line | BioXtra |
| Quality Level | 200 ![]() |
| reaction suitability | reagent type: reductant |
| SMILES string | O[C@H](CS)[C@H](O)CS |
| solubility | H2O: 0.1 M, clear, colorless |
| storage temp. | 2-8°C |
| Application: | An excellent reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides. DTT is effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N′-bis(acryloyl)cystami |
| Packaging: | 1, 5, 25 g in glass bottle |
| Symbol | ![]() GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H302 - H315 - H318 |
| Precautionary statements | P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 22-36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | UN 3335 |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.0% (titration) |
| mp | 41-44 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352201 |



