DL-Dithiothreitol
SIAL/D5545 - BioXtra, ≥99.0% (titration)
Synonym: threo-
CAS Number: 3483-12-3
Empirical Formula (Hill Notation): C4H10O2S2
Molecular Weight: 154.25
EC Number: 222-468-7
MDL Number: MFCD00004877
Linear Formula: HSCH2CH(OH)CH(OH)CH2SH
Product Type: Chemical
absorption | ≤0.100 at 280 in H2O at 0.1 M |
≤0.400 at 260 in H2O at 0.1 M | |
anion traces | sulfate (SO42-): ≤0.005% |
assay | ≥99.0% (titration) |
cation traces | Al: ≤0.0005% |
As: ≤0.0001% | |
Ba: ≤0.0005% | |
Bi: ≤0.0005% | |
Ca: ≤0.001% | |
Cd: ≤0.0005% | |
Co: ≤0.0005% | |
Cr: ≤0.0005% | |
Cu: ≤0.0005% | |
Fe: ≤0.0005% | |
K: ≤0.005% | |
Li: ≤0.0005% | |
Mg: ≤0.0005% | |
Mn: ≤0.0005% | |
Mo: ≤0.0005% | |
Na: ≤0.1% | |
Ni: ≤0.0005% | |
Pb: ≤0.0005% | |
Sr: ≤0.0005% | |
Zn: ≤0.0005% | |
form | powder |
impurities | Insoluble matter, passes filter test |
≤0.3% 4,5-dihydroxy-1,2-dithian |
|
InChI | 1S/C4H10O2S2/c5-3(1-7)4(6 |
InChI key | VHJLVAABSRFDPM-QWWZWVQMSA |
mp | 41-44 °C (lit.) |
pH | 4.0-6.0 (20-25 °C, 0.1 m in H2O) |
product line | BioXtra |
Quality Level | 200 |
reaction suitability | reagent type: reductant |
SMILES string | O[C@H](CS)[C@H](O)CS |
solubility | H2O: 0.1 M, clear, colorless |
storage temp. | 2-8°C |
Application: | An excellent reagent for maintaining SH groups in reduced state; quantitatively reduces disulfides. DTT is effective in sample buffers for reducing protein disulfide bonds prior to SDS-PAGE. DTT can also be used for reducing the disulfide bridge of the cross-linker N,N′-bis(acryloyl)cystami |
Packaging: | 1, 5, 25 g in glass bottle |
Symbol | GHS05,GHS07 |
Signal word | Danger |
Hazard statements | H302 - H315 - H318 |
Precautionary statements | P264 - P270 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xn |
Risk Statements | 22-36/37/38 |
Safety Statements | 26-36 |
RIDADR | UN 3335 |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99.0% (titration) |
mp | 41-44 °C (lit.) |
Storage Temp. | 2-8°C |
UNSPSC | 12352201 |