Dextran sulfate sodium salt from Leuconostoc spp.
SIAL/D6924 - average mol wt 9,000-20,000
CAS Number: 9011-18-1
MDL Number: MFCD00081551
Product Type: Chemical
biological source | bacterial (Leuconostoc mesenteroides) |
composition | Sulfur Content, 16.0-19.0% |
form | powder |
mol wt | average mol wt 9,000-20,000 |
optical activity | [α]/D 90 to 105 °, c = 6% (w/v) |
Quality Level | 200 ![]() |
solubility | H2O: 100 mg/mL |
Application: | Dextran sulfate sodium salt from Leuconostoc spp. has been used: • to evaluate the participation of sulfated glycans on the interaction of recombinant human proacrosin/acrosin with zona pellucida (ZP) glycoproteins • to inject into the vitreous cavity of embryonic day five chick embryos to assess the eye size and to study its impact on cell proliferation in the retina • to test the structural specificity of binding of TNF-stimulated gene 6 (TSG-6) to immobilized hyaluronan (HA) |
Biochem/physiol Actions: | Dextran sulfate may exhibit anti-coagulant and antiviral properties. It may also help to lower cholesterol levels. It is extensively used as a plasma volume expander and fibrinolytic in the medical field. Dextran sulfate can also be used as a cross-linker for chitosan (CH). |
General description: | Dextran sulfate sodium is a natural polymer of α-1,6-D-glucopyranose. It is a hydrophilic, biodegradable, and biocompatible polyanionic polymer. This highly branched polysaccharide has 1,6 and 1,4 glycosidic linkages, consisting of 2.3 sulfate groups per glucosyl unit. |
Packaging: | 1, 10 g in poly bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
UNSPSC | 12352201 |