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Erythromycin

SIAL/E0774 - meets USP testing specifications

Synonym: Erythromycin A

CAS Number: 114-07-8
Empirical Formula (Hill Notation): C37H67NO13
Molecular Weight: 733.93
EC Number: 204-040-1
MDL Number: MFCD00084654
Linear Formula: C37H67NO13
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-E0774-5G 5 g
$106.00
1/EA
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45-E0774-25G 25 g
$403.00
1/EA
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45-E0774-100G 100 g
$982.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: E0774-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: E0774-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: E0774-5G

 

agency meets USP testing specifications
  USP/NF
antibiotic activity spectrum Gram-negative bacteria
  Gram-positive bacteria
application(s) pharmaceutical (small molecule)
form solid
InChI 1S/C37H67NO13/c1-14-25-37(10,45)30(41)20(4)27(39)18(2)16-35(8,44)32(51-34-28(40)24(38(11)12)15-19(3)47-34)21(5)29(22(6)33(43)49-25)50-26-17-36(9,46-13)31(42)23(7)48-26/h18-26,28-32,34,40-42,44-45H,14-17H2,1-13H3/t18-,19-,20+,21+,22-,23+,24+,25-,26+,28-,29+,30-,31+,32-,34+,35-,36-,37-/m1/s1
InChI key ULGZDMOVFRHVEP-RWJQBGPGSA-N
mode of action protein synthesis | interferes
optical activity [α]/D -78 to --71°
Quality Level 200 
SMILES string CC[C@H]1OC(=O)[C@H](C)[C@@H](O[C@H]2C[C@@](C)(OC)[C@@H](O)[C@H](C)O2)[C@H](C)[C@@H](O[C@@H]3O[C@H](C)C[C@@H]([C@H]3O)N(C)C)[C@](C)(O)C[C@@H](C)C(=O)[C@H](C)[C@@H](O)[C@]1(C)O
solubility ethanol: 50 mg/mL, clear to slightly hazy, colorless to faintly yellow
Application: Erythromycin is an antibiotic produced by growth of certain strains of Streptomyces erythreus. This product is composed largely of erythromycin A with small amounts of erythromycins B and C and is recommended for concentration at 100 mg/L. Concentrations between 50 and 200 mg/L have also proven effective in controlling bacterial growth. Erythromycin has been used as a motilin receptor agonist, to block respiratory glycoconjugate secretion in human airways in vitro, and for selecting plasmid-cured and recombinant lactococcus lactis MG1363 strains.
Biochem/physiol Actions: Mode of Action: Erythromycin acts by inhibiting elongation at the transpeptidation step, specifically aminoacyl translocation from the A-site to P-site by binding to the 50s subunit of the bacterial 70s rRNA complex.

Antimicrobial Spectrum: This product acts against both gram-negative and gram-positive bacteria.
Caution: This product is stable in solution at 37°C for 3 days. Stock solutions should be stored at 2-8°C.
General description: Chemical structure: macrolide
Packaging: 5, 25, 100 g in poly bottle
Preparation Note: This product is soluble in water at 2 mg/mL, with a 0.067% solution in water yielding a pH of 8.0-10.5. It is also soluble in ethanol at 50 mg/mL, yielding a clear, colorless to faint yellow solution. It is freely soluble in alcohol, acetone, chloroform, acetonitrile and ethyl acetate but forms salts with acids. All solutions should be protected from light.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 51101500

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