N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride
SIAL/E1769 - BioXtra
Synonym: N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride; EDAC; EDC; EDC hydrochloride; WSC hydrochloride
CAS Number: 25952-53-8
Empirical Formula (Hill Notation): C8H17N3 · HCl
Molecular Weight: 191.70
EC Number: 247-361-2
MDL Number: MFCD00012503
Linear Formula: C8H17N3 · HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: E1769-25G
This image depicts SKU: E1769-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: E1769-1G
This image depicts SKU: E1769-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: E1769-5G
This image depicts SKU: E1769-5G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: E1769-10G
This image depicts SKU: E1769-10G
| anion traces | sulfate (SO42-): ≤0.05% |
| cation traces | Al: ≤0.0005% |
| Ca: ≤0.0005% | |
| Cu: ≤0.0005% | |
| Fe: ≤0.0005% | |
| K: ≤0.005% | |
| Mg: ≤0.0005% | |
| Na: ≤0.005% | |
| NH4+: ≤0.05% | |
| Pb: ≤0.001% | |
| Zn: ≤0.0005% | |
| form | powder |
| ign. residue | ≤0.1% |
| impurities | ≤0.005% Phosphorus (P) |
| ≤0.1% Insoluble matter | |
| InChI | 1S/C8H17N3.ClH/c1-4-9-8-1 |
| InChI key | FPQQSJJWHUJYPU-UHFFFAOYSA |
| mp | 110-115 °C (lit.) |
| product line | BioXtra |
| Quality Level | 200  |
| SMILES string | Cl.CCN=C=NCCCN(C)C |
| solubility | H2O: 0.5 M, clear to very slightly hazy, colorless to very faintly yellow |
| storage temp. | −20°C |
| Application: | N-(3-Dimethylaminopropyl) • for post-fixation and crosslinking of small ribonucleic acid (RNAs) species from formalin fixed paraffin embedded (FFPE) tissues, for fluorescent in situ hybridisation (FISH) and immunofluorescence (IF) signals • for cross-linking of nanofiber matrices with mouse lung extract • for activation of substrate XNA oligonucleotides |
| Biochem/physiol Actions: | Water soluble condensing reagent. EDAC is generally utilized as a carboxyl activating agent for amide bonding with primary amines. In addition, it will react with phosphate groups. EDAC has been used in peptide synthesis; crosslinking proteins to nucleic acids; and preparation of immunoconjugates as examples. Typically, EDAC is utilized in the pH range 4.0-6.0 without buffers. In particular, amine and carboxylate buffers should be avoided. |
| Packaging: | 1, 5, 10, 25 g in poly bottle |
| Symbol |    GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H302 - H311 - H315 - H317 - H373 - H410 |
| Precautionary statements | P260 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P314 |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41 |
| Safety Statements | 26-36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 110-115 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12161700 |