Ethylenediaminetetraacetic acid disodium salt dihydrate

SIAL/E4884 - ACS reagent, 99.0-101.0%

Synonym: Disodium ethylenediaminetetraacetate dihydrate; EDTA disodium salt; EDTA-Na₂; Edathamil; Edetate disodium salt dihydrate; Sequestrene Na₂

CAS Number: 6381-92-6
Empirical Formula (Hill Notation): C₁₀H₁₄N₂Na₂O₈ · 2H₂O
Molecular Weight: 372.24
EC Number: 205-358-3
Linear Formula: C₁₀H₁₄N₂Na₂O₈ · 2H₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-E4884-100G	100 g	$59.20 1/EA	Add To Favorites
45-E4884-500G	500 g	$166.00 1/EA	Add To Favorites

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This image depicts SKU: E4884-100G

Properties
Descriptions
Safety Info.
Basic Data

assay	99.0-101.0%
cation traces	Fe: ≤0.01%
	heavy metals (as Pb): ≤0.005%
form	solid
grade	ACS reagent
impurities	≤0.005% Insoluble matter
	≤0.1% Nitrilotriacetic acid ([HOCOCH₂]₃N)
InChI	1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;21H2/q;2+1;;/p-2
InChI key	OVBJJZOQPCKUOR-UHFFFAOYSA-L
mp	248 °C (dec.) (lit.)
pH	4.0-6.0 (25 °C, 5%)
Quality Level	200
SMILES string	O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
solubility	H₂O: 100 g/L at 20 °C
storage temp.	room temp

Application:	Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.
Application:	Ethylenediaminetetraacetic acid disodium salt dehydrate has been used as a component: • of radioimmunoprecipitation assay buffer (RIPA buffer) for preparation of C2C12 mouse skeletal myoblasts whole cell lysate • of lysis buffer and IgG resin wash and equilibration buffer for the purification of human proteasome regulatory particles (RPs) • of M-buffer for the isolation of human cardiomyocyte progenitor cells (CMPCs) from fetal heart
Biochem/physiol Actions:	Ethylenediaminetetraacetic acid (EDTA) is an anticoagulant, majorly used in preventing clotting of blood. EDTA may trigger aggregation of platelets resulting in pseudothrombocytopenia. EDTA along with tetracycline serves as a root conditioning agent and provides relief in gum infection. EDTA-tetracycline therapy decreases coronary artery calcium levels in atherosclerosis. Calcium disodium EDTA administration is effective in slowing down the progression of chronic kidney disease. It also enhances the antimicrobial functionality of lysozyme and improves shelf life of cheese.
General description:	EDTA is a chelator of divalent cations. It inhibits enzymes, such as metalloproteases, that require divalent cations for activity.
Packaging:	100, 500 g in poly bottle

Symbol	GHS07,GHS08
Signal word	Warning
Hazard statements	H332 - H373 - H412
Precautionary statements	P260 - P271 - P273 - P304 + P340 + P312 - P314 - P501
Hazard Codes	Xn
Risk Statements	20-48/20
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	99.0-101.0%
mp	248 °C (dec.) (lit.)
Storage Temp.	room temp
UNSPSC	12352200

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