N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride
SIAL/E6383 - crystalline
Synonym: EDC; N-Ethyl-N′-(3-dimethylaminopropyl)carbodiimide hydrochloride; EDAC; EDC; EDC hydrochloride; WSC hydrochloride
CAS Number: 25952-53-8
Empirical Formula (Hill Notation): C8H17N3 · HCl
Molecular Weight: 191.70
EC Number: 247-361-2
MDL Number: MFCD00012503
Linear Formula: C8H17N3 · HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E6383-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: E6383-5G
| form | crystalline |
| InChI | 1S/C8H17N3.ClH/c1-4-9-8-1 |
| InChI key | FPQQSJJWHUJYPU-UHFFFAOYSA |
| mp | 110-115 °C (lit.) |
| Quality Level | 200  |
| reaction suitability | reagent type: cross-linking reagent reaction type: Peptide Synthesis |
| SMILES string | Cl.CCN=C=NCCCN(C)C |
| solubility | H2O: ≤100 mg/mL |
| storage temp. | −20°C |
| Application: | N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride has been used: • for the immobilisation of trypsin onto self-assembled monolayers (SAMs) • as a component for the preparation of collagen matrices • for the preparation of phosphoethanolamine(PEt)- |
| Biochem/physiol Actions: | Water soluble condensing reagent. EDAC is generally utilized as a carboxyl activating agent for amide bonding with primary amines. In addition, it will react with phosphate groups. EDAC has been used in peptide synthesis; crosslinking proteins to nucleic acids; and preparation of immunoconjugates as examples. Typically, EDAC is utilized in the pH range 4.0-6.0 without buffers. In particular, amine and carboxylate buffers should be avoided. |
| Packaging: | 1, 5 g in glass bottle |
| Symbol |    GHS06,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H302 - H311 - H315 - H317 - H373 - H410 |
| Precautionary statements | P260 - P273 - P280 - P301 + P312 - P302 + P352 + P312 - P314 |
| Hazard Codes | Xi |
| Risk Statements | 37/38-41 |
| Safety Statements | 26-36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 110-115 °C (lit.) |
| Storage Temp. | −20°C |
| UNSPSC | 12352200 |