Ethylenediaminetetraacetic acid disodium salt solution

SIAL/E7889 - for molecular biology, 0.5 M in H₂O, DNase, RNase, NICKase and protease, none detected

Synonym: (Ethylenedinitrilo)tetraacetic acid disodium salt; EDTA disodium salt; EDTA-Na₂

CAS Number: 139-33-3
Empirical Formula (Hill Notation): C₁₀H₁₄N₂Na₂O₈
Molecular Weight: 336.21
MDL Number: MFCD00070672
Linear Formula: [-CH₂N(CH₂CO₂Na)CH₂CO₂H]₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-E7889-100ML	100 mL	$75.30 1/EA	Add To Favorites
45-E7889-1L	1 L	$372.00 1/EA	Add To Favorites

Representative product in the bottle

Properties
Descriptions
Safety Info.
Basic Data

concentration	0.5 M in H₂O
foreign activity	DNase, RNase, NICKase and protease, none detected
grade	for molecular biology
InChI	1S/C10H16N2O8.2Na/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;/q;2*+1/p-2
InChI key	ZGTMUACCHSMWAC-UHFFFAOYSA-L
Quality Level	300
SMILES string	[Na+].[Na+].OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
sterility	0.2 μm filtered

Application:	Ethylenediaminetetraacetic acid disodium salt solution has been used: • in Tris hydrochloric acid (HCl) for digesting proteinase-K to determine the amount of DNA in the corneal sample • with papain to digest corneal samples for the quantification of glycosaminoglycan (GAG) content • in pretreatment for detaching epithelial cells grown to 80% confluency • to prepare stock solutions for lysis buffer • in the preparation of urea lysis buffer
Biochem/physiol Actions:	Ethylenediaminetetraacetic acid (EDTA) is used in the treatment of patients poisoned with heavy metal ions. This permeating and sensitizing agent is also used for treating biofilm-associated conditions in dentistry, medical devices, and veterinary medicine. EDTA is currently formulated into commercially available wound dressings in human medicine to regulate matrix metalloproteinases (MMPs) and manage wound infections. It is combined with other active agents to regulate microorganisms and biofilms, including citric acid, alcohol, antibiotics, polyhexamethylene biguanide (PHMB) quaternary ammonium compounds, iodine, silver, surfactants, and other antiseptics. For hematological testing, EDTA acts as an anticoagulant due to its ability in preserving the cellular components and morphology of blood cells.
General description:	Ethylenediaminetetraacetic acid (EDTA) is a polyprotic acid. The four carboxylic acid and two amine groups with lone-pair electrons of EDTA can chelate calcium and several other metal ions.
General description:	Ethylenediaminetetraacetic acid disodium salt solution is a chelating agent suitable for molecular biology applications.
Preparation Note:	Prepared in 18 megohm water with Molecular Biology Reagent EDTA (E 5134)

Symbol	GHS08
Signal word	Warning
Hazard statements	H373
Precautionary statements	P260 - P314 - P501
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

UNSPSC

12352200

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