Ethylenediaminetetraacetic acid disodium salt dihydrate

SIAL/ED2SS - reagent grade, 98.5-101.5% (titration)

Synonym: Disodium ethylenediaminetetraacetate dihydrate; EDTA disodium salt; EDTA-Na₂; Edathamil; Edetate disodium salt dihydrate; Sequestrene Na₂

CAS Number: 6381-92-6
Empirical Formula (Hill Notation): C₁₀H₁₄N₂Na₂O₈ · 2H₂O
Molecular Weight: 372.24
EC Number: 205-358-3
Linear Formula: C₁₀H₁₄N₂Na₂O₈ · 2H₂O
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-ED2SS-50G	50 g	$42.10 1/EA	Add To Favorites
45-ED2SS-100G	100 g	$71.40 1/EA	Add To Favorites
45-ED2SS-250G	250 g	$133.00 1/EA	Add To Favorites
45-ED2SS-500G	500 g	$265.40 1/EA	Add To Favorites
45-ED2SS-1KG	1 kg	$356.08 1/EA	Add To Favorites
45-ED2SS-2.5KG	2.5 kg	$497.00 1/EA	Add To Favorites
45-ED2SS-5KG	5 kg	$856.00 1/EA	Add To Favorites

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This image depicts SKU: ED2SS-100G

Properties
Descriptions
Safety Info.
Basic Data

assay	98.5-101.5% (titration)
biological source	synthetic (organic)
form	powder
grade	reagent grade
InChI	1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;21H2/q;2+1;;/p-2
InChI key	OVBJJZOQPCKUOR-UHFFFAOYSA-L
mp	248 °C (dec.) (lit.)
Quality Level	200
SMILES string	O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
solubility	H₂O: soluble, clear, colorless
storage temp.	room temp

Application:	Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.
Application:	Ethylenediaminetetraacetic acid disodium salt dihydrate has been used as a component of the plasma membrane resuspension buffer, inhibitor′s preservative solution (IS) and luciferase activity assay mix.
Biochem/physiol Actions:	Zinc-dependent metalloproteinases, as well as other proteases that are stabilized by calcium, can be effectively inhibited by chelation of divalent metal ions with EDTA. Other chelators such as EGTA, specific for calcium, and 1,10-phenanthroline, highly specific for zinc, can be used to target these two different types of proteases.
General description:	Ethylenediaminetetraacetic acid (EDTA) is an aminopolycarboxylic acid and a hexadentate ligand. It chelates with metal ions to form an octahedral complex especially with cations. Ethylenediaminetetraacetic acid disodium salt (EDTA) is a blood anticoagulant and contributes to the pathogenesis of pseudothrombocytopenia. It chelates with calcium in the blood and inhibits clotting and is routinely used in haematological tests. It enhances the antibacterial activity of lysozyme. EDTA used in chelation therapy chelates with calcium and favors dilation of artery, solubilisation of atheromatous plaques in atherosclerotic vascular disease. EDTA chelation therapy protects from lipid peroxidation events in liver fibrosis.
Packaging:	1 kg in poly bottle
Packaging:	2.5, 5 kg in poly drum
Packaging:	50, 100, 250, 500 g in poly bottle

Symbol	GHS07,GHS08
Signal word	Warning
Hazard statements	H332 - H373 - H412
Precautionary statements	P260 - P271 - P273 - P304 + P340 + P312 - P314 - P501
Hazard Codes	Xn
Risk Statements	20-48/20
RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	98.5-101.5% (titration)
mp	248 °C (dec.) (lit.)
Storage Temp.	room temp
UNSPSC	12352200

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