Fluorescein sodium salt
SIAL/F6377 - used as fluorescent tracer
Synonym: Acid Yellow 73; D&C;Yellow No. 8; NaFl; NaFluo; Sodium fluorescein; Uranine
CAS Number: 518-47-8
Empirical Formula (Hill Notation): C20H10Na2O5
Molecular Weight: 376.27
EC Number: 208-253-0
MDL Number: MFCD00167039
Linear Formula: C20H10Na2O5
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F6377-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F6377-100G
| application(s) | diagnostic assay manufacturing hematology histology |
| color | orange to brown |
| density | 0.78 g/cm3 at 29.6 °C (85.3 °F at 699.7 hPa) |
| fluorescence | λex 460 nm; λem 515 nm(lit.) |
| form | powder |
| InChI | 1S/C20H12O5.2Na/c21-11-5- |
| InChI key | RGPLGPBQJOQFJS-UHFFFAOYSA |
| mp | >300 °C |
| pH | 8.3 (20 °C, 10 g/L) |
| Quality Level | 200  |
| SMILES string | [Na+].[Na+].[O-]c1ccc2c(O |
| solubility | H2O: 1 mg/mL |
| storage temp. | room temp |
| Application: | Fluorescein sodium salt has been used as a solute to study microvessel permeability. It has been used as a test molecule to study blood barrier penetration. |
| Application: | Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius. Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models. The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes. Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP). |
| General description: | Fluorescein is a xanthene dye and is a common labeling agent in biology. |
| Packaging: | 100, 500 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 423.7 °F - Pensky-Martens c |
| Flash Point(C) | 217.6 °C - Pensky-Martens c |
| mp | >300 °C |
| Density | 0.78 g/cm3 at 29.6 °C (85.3 °F at 699.7 hPa) |
| Storage Temp. | room temp |
| Colour Index Number | 45350 |
| UNSPSC | 12171500 |