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Fluorescein sodium salt

SIAL/F6377 - used as fluorescent tracer

Synonym: Acid Yellow 73; D&C;Yellow No. 8; NaFl; NaFluo; Sodium fluorescein; Uranine

CAS Number: 518-47-8
Empirical Formula (Hill Notation): C20H10Na2O5
Molecular Weight: 376.27
EC Number: 208-253-0
MDL Number: MFCD00167039
Linear Formula: C20H10Na2O5
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-F6377-100G 100 g
 $42.60
1/EA		 Add To Favorites
45-F6377-500G 500 g
 $146.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F6377-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: F6377-100G

 

application(s) diagnostic assay manufacturing
hematology
histology
fluorescence λex 460 nm; λem 515 nm(lit.)
form powder
InChI 1S/C20H12O5.2Na/c21-11-5-7-15-17(9-11)24-18-10-12(22)6-8-16(18)20(15)14-4-2-1-3-13(14)19(23)25-20;;/h1-10,21-22H;;/q;2*+1/p-2
InChI key RGPLGPBQJOQFJS-UHFFFAOYSA-L
mp >300 °C
pH 8.3 (20 °C, 10 g/L)
Quality Level 200 
SMILES string [Na+].[Na+].[O-]c1ccc2c(Oc3cc([O-])ccc3C24OC(=O)c5ccccc45)c1
storage temp. room temp
Application: Fluorescein sodium salt has been used as a solute to study microvessel permeability. It has been used as a test molecule to study blood barrier penetration.
Application: Water soluble fluorescent dye used in permeability and vascular perfusion studies due to its small molecular radius. Sodium fluorescein is used as a fluorescent tracer to study blood-brain barrier (BBB) and blood-spinal cord barrier (BSCB) permeability in rodent models. The dye was used as a probe substrate in the study of organic anion transporting polypeptide (OATP) mediated drug transport in hepatocytes. Sodium fluorescein was also used to monitor in situ solute transportation into bone through fluorescence recovery after photobleaching (FRAP).
General description: Fluorescein is a xanthene dye and is a common labeling agent in biology.
Packaging: 100, 500 g in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) 423.7 °F - Pensky-Martens c
Flash Point(C) 217.6 °C - Pensky-Martens c
mp >300 °C
Storage Temp. room temp
Colour Index Number 45350
UNSPSC 12171500

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