Gentamicin solution
SIAL/G1522 - Hybri-Max™, 0.1 μm filtered, 50 mg/mL gentamicin, BioReagent, suitable for hybridoma
Synonym: Garamycin; Gentiomycin C
CAS Number: 1405-41-0
MDL Number: MFCD00270181
Product Type: Chemical
antibiotic activity spectrum | Gram-negative bacteria |
Gram-positive bacteria | |
mycoplasma | |
color | colorless to light yellow |
concentration | 50 mg/mL gentamicin |
density | 1.000 g/cm3 |
form | liquid |
grade | Hybri-Max™ |
impurities | endotoxin, tested |
InChI | 1S/C21H43N5O7.C20H41N5O7. |
InChI key | RDEIXVOBVLKYNT-HDZPSJEVSA |
mode of action | protein synthesis | interferes |
product line | BioReagent |
quality | Prepared in tissue culture grade water. |
Quality Level | 300 |
SMILES string | OS(O)(=O)=O.CN[C@@H]1[C@@ |
sterility | 0.1 μm filtered |
storage temp. | 2-8°C |
technique(s) | cell culture | hybridoma: suitable |
Application: | Gentamicin solution has been used to study its dose-related antipruritic effects on serotonin (5-HT)-induced scratching model. It has also been used in electrophysiological analysis. |
Biochem/physiol Actions: | Mode of Action: Gentamicin inhibits protein synthesis by binding to the 30S subunit of the ribosome. Antimicrobial spectrum: Includes Gram-negative and Gram-positive bacteria, including strains resistant to tetracycline, chloramphenicol, kanamycin and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus and Streptococcus. |
Caution: | The product is stable at 37° for 5 days and is stored at 2-8°C. |
Components: | Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiresing five equivalents of sulfuric acid per mole of gentamicin base. |
General description: | Chemical structure: aminoglycoside |
Legal Information: | Hybri-Max is a trademark of Sigma-Aldrich Co. LLC |
RIDADR | NONH for all modes of transport |
WGK Germany | nwg |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Density | 1.000 g/cm3 |
Storage Temp. | 2-8°C |
UNSPSC | 12352207 |