Gentamicin solution

SIAL/G1522 - Hybri-Max^™, 50 mg/mL gentamicin, 0.1 μm filtered, BioReagent, suitable for hybridoma

Synonym: Garamycin; Gentiomycin C

CAS Number: 1405-41-0
MDL Number: MFCD00270181
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-G1522-10ML	10 mL	$191.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

antibiotic activity spectrum	Gram-negative bacteria
	Gram-positive bacteria
	mycoplasma
color	colorless to light yellow
concentration	50 mg/mL gentamicin
density	1.000 g/cm³
form	liquid
grade	Hybri-Max^™
impurities	endotoxin, tested
InChI	1S/C21H43N5O7.C20H41N5O7.C19H39N5O7.H2O4S/c1-9(25-3)13-6-5-10(22)19(31-13)32-16-11(23)7-12(24)17(14(16)27)33-20-15(28)18(26-4)21(2,29)8-30-20;1-8(21)12-5-4-9(22)18(30-12)31-15-10(23)6-11(24)16(13(15)26)32-19-14(27)17(25-3)20(2,28)7-29-19;1-19(27)7-28-18(13(26)16(19)24-2)31-15-11(23)5-10(22)14(12(15)25)30-17-9(21)4-3-8(6-20)29-17;1-5(2,3)4/h9-20,25-29H,5-8,22-24H2,1-4H3;8-19,25-28H,4-7,21-24H2,1-3H3;8-18,24-27H,3-7,20-23H2,1-2H3;(H2,1,2,3,4)/t9-,10-,11+,12-,13+,14+,15-,16-,17+,18-,19-,20-,21+;8-,9-,10+,11-,12+,13+,14-,15-,16+,17-,18-,19-,20+;8-,9+,10-,11+,12-,13+,14+,15-,16+,17+,18+,19-;/m110./s1
InChI key	RDEIXVOBVLKYNT-HDZPSJEVSA-N
mode of action	protein synthesis \| interferes
product line	BioReagent
quality	Prepared in tissue culture grade water.
Quality Level	300
SMILES string	OS(O)(=O)=O.CN[C@@H]1[C@@H](O)[C@H](OC[C@]1(C)O)O[C@H]2[C@H](N)C[C@H](N)[C@@H](O[C@H]3O[C@H](CN)CC[C@H]3N)[C@@H]2O.CN[C@@H]4[C@@H](O)[C@H](OC[C@]4(C)O)O[C@H]5[C@H](N)C[C@H](N)[C@@H](O[C@H]6O[C@@H](CC[C@H]6N)[C@@H](C)N)[C@@H]5O.CN[C@H](C)[C@@H]7CC[C@@H](N)[C@H](O7)O[C@@H]8[C@@H](N)C[C@@H](N)[C@H](O[C@H]9OC[C@](C)(O)[C@H](NC)[C@H]9O)[C@H]8O
sterility	0.1 μm filtered
storage temp.	2-8°C
technique(s)	cell culture \| hybridoma: suitable

Application:	Gentamicin solution has been used to study its dose-related antipruritic effects on serotonin (5-HT)-induced scratching model. It has also been used in electrophysiological analysis.
Biochem/physiol Actions:	Mode of Action: Gentamicin inhibits protein synthesis by binding to the 30S subunit of the ribosome. Antimicrobial spectrum: Includes Gram-negative and Gram-positive bacteria, including strains resistant to tetracycline, chloramphenicol, kanamycin and colistin, particularly strains of Pseudomonas, Proteus, Staphylococcus and Streptococcus.
Caution:	The product is stable at 37° for 5 days and is stored at 2-8°C.
Components:	Gentamicin is an aminoglycoside complex produced by fermentation of Micromonospora purpurea or M. echinospora. It is used as the sulfate salt. There are three components, each consisting of five basic nitrogens and requiresing five equivalents of sulfuric acid per mole of gentamicin base.
General description:	Chemical structure: aminoglycoside
Legal Information:	Hybri-Max is a trademark of Sigma-Aldrich Co. LLC

RIDADR	NONH for all modes of transport
WGK Germany	nwg
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Density	1.000 g/cm³
Storage Temp.	2-8°C
UNSPSC	12352203

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