L-Glutathione reduced

SIAL/G4251 - ≥98.0%

Synonym: γ-L-Glutamyl-L-cysteinyl-glycine; GSH

CAS Number: 70-18-8
Empirical Formula (Hill Notation): C₁₀H₁₇N₃O₆S
Molecular Weight: 307.32
EC Number: 200-725-4
MDL Number: MFCD00065939
Linear Formula: H₂NCH(CO₂H)CH₂CH₂CONHCH(CH₂SH)CONHCH₂CO₂H
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-G4251-10MG	10 mg	$23.70 1/EA	Add To Favorites
45-G4251-300MG	300 mg	$29.60 1/EA	Add To Favorites
45-G4251-1G	1 g	$34.20 1/EA	Add To Favorites
45-G4251-5G	5 g	$66.90 1/EA	Add To Favorites
45-G4251-10G	10 g	$102.00 1/EA	Add To Favorites
45-G4251-25G	25 g	$185.00 1/EA	Add To Favorites
45-G4251-50G	50 g	$333.00 1/EA	Add To Favorites
45-G4251-100G	100 g	$620.00 1/EA	Add To Favorites
45-G4251-250G	250 g	$1300.00 1/EA	Add To Favorites
45-G4251-500G	500 g	$2350.00 1/EA	Add To Favorites

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This image depicts SKU: G4251-50G

Properties
Descriptions
Safety Info.
Basic Data

application(s)	detection
assay	≥98.0%
color	white
form	powder
InChI	1S/C10H17N3O6S/c11-5(10(18)19)1-2-7(14)13-6(4-20)9(17)12-3-8(15)16/h5-6,20H,1-4,11H2,(H,12,17)(H,13,14)(H,15,16)(H,18,19)/t5-,6-/m0/s1
InChI key	RWSXRVCMGQZWBV-WDSKDSINSA-N
mp	192-195 °C (dec.) (lit.)
Quality Level	300
SMILES string	N[C@@H](CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O)C(O)=O
storage temp.	2-8°C

Amino Acid Sequence:	γ-Glu-Cys-Gly
Application:	L-Glutathione (GSH) reduced has been used in the elution buffer to elute GST (glutathione S-transferase)-fused proteins using glutathione-agarose beads. It has been used to prepare a standard curve for GSH analyses.
Application:	May be used at 5-10 mM to elute glutathione S-transferase (GST) from glutathione agarose.
Biochem/physiol Actions:	Endogenous antioxidant that plays a major role in reducing reactive oxygen species formed during cellular metabolism and the respiratory burst. Glutathione-S-transferase catalyzes the formation of glutathione thioethers with xenobiotics, leukotrienes, and other molecules that have an electrophilic center. Glutathione also forms disulfide bonds with cysteine residues in proteins. Via these mechanisms, it can have the paradoxical effect of reducing the efficacy of anti-cancer agents.
Biochem/physiol Actions:	Reduced L-glutathione (GSH) is a thiol compound and is associated with catabolism and transportation. Plasma GSH levels are associated with Parkinson′s diseases, Alzheimer′s, diabetes, macular degeneration, and HIV (human immunodeficiency virus) disease.
Packaging:	1, 5, 10, 25, 50, 100, 250, 500 g in poly bottle
Packaging:	10 mg in glass bottle
Packaging:	300 mg in poly bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 2
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98.0%
mp	192-195 °C (dec.) (lit.)
Storage Temp.	2-8°C
UNSPSC	12352209

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