Glutaraldehyde solution
SIAL/G5882 - Grade I, 25% in H2O, specially purified for use as an electron microscopy fixative
Synonym: Glutaric dialdehyde solution; Pentane-1,5-dial
CAS Number: 111-30-8
Empirical Formula (Hill Notation): C5H8O2
Molecular Weight: 100.12
MDL Number: MFCD00007025
Linear Formula: OHC(CH2)3CHO
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G5882-100ML.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G5882-1L.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G5882-80ML.
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G5882-50ML
| application(s) | cell analysis |
| color | colorless |
| concentration | 25% in H2O |
| form | liquid |
| InChI | 1S/C5H8O2/c6-4-2-1-3-5-7/ |
| InChI key | SXRSQZLOMIGNAQ-UHFFFAOYSA |
| mp | -10 °C ((14 °F )) |
| Quality Level | 300  |
| shipped in | dry ice |
| SMILES string | [H]C(CCCC([H])=O)=O |
| solubility | water: soluble at 20 °C |
| storage temp. | −20°C |
| technique(s) | electron microscopy: suitable |
| electron microscopy: suitable (fixative) | |
| type | Grade I |
| useful pH range | 2.9 |
| Application: | Glutaraldehyde solution has been used: • to fix the blood samples for scanning electron microscopy (SEM) • to fix scaffold pieces for SEM analysis • in drug treatments to treat K562 (leukemia) cells to permanently cross-link cell components |
| Biochem/physiol Actions: | Glutaraldehyde can be used in biomedical research to fix cells. It can also be used as a tool to investigate healthy and pathologic red blood cells. Medical equipment like spirometry tubing, endoscopes, dialyzers, hemodialysis proportioning and dialysate delivery systems, endocavitary probes, transducers, anesthesia and respiratory therapy equipment, and reuse of laparoscopic disposable plastic trocars can be disinfected with glutaraldehyde. |
| Features and Benefits: | • Versatile and adaptable for wide variety of research applications • Ready-made solution reduces the need for preparation time |
| General description: | Glutaraldehyde (Glutaric dialdehyde, Pentane-1,5-dial) is an aliphatic dialdehyde widely utilized as a versatile biochemical reagent. Glutaraldehyde solutions contain both monomers and polymers with the difference in their fixation properties. Its applications include serving as a protein crosslinker, facilitating enzyme immobilization in microscopy, histochemistry, and cytochemistry. This compound acts as an amine-reactive homobifunctional crosslinker and a cell fixative before SDS-PAGE, staining, or electron microscopy, making it suitable for diverse morphological studies. Glutaraldehyde efficiently crosslinks amine and hydrazine derivatives to proteins and other amine-containing polymers. Notably, it has been used in certain reactions to directly couple biotin hydrazides to nucleic acids, suggesting potential applications in conjugating fluorescent hydrazides and hydroxylamines to DNA. In histology studies, Glutaraldehyde is employed to preserve tissue sections, preparing them for closer examination. |
| Other Notes: | 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research  |
| Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
| Other Notes: | Recommended for techniques demanding high purity. |
| Other Notes: | To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page. |
| Packaging: | 1 L in glass bottle |
| Packaging: | 10×1 mL in ampule |
| Packaging: | 50, 80, 100 mL in glass bottle |
| Symbol |     GHS05,GHS07,GHS08,GHS09 |
| Signal word | Danger |
| Hazard statements | H302 + H332 - H314 - H317 - H334 - H335 - H410 |
| Precautionary statements | P273 - P280 - P301 + P312 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 22-23-34-42/43 |
| Safety Statements | 23-26-36/37/39-45 |
| RIDADR | UN3265 - class 8 - PG 2 - EHS - Corrosive liquid, acidic, organi |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Supplemental Hazard Statements | EUH071 |
| mp | -10 °C ((14 °F )) |
| Storage Temp. | −20°C |
| UNSPSC | 12352114 |