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Guanidine thiocyanate

SIAL/G6639 - ≥97% (titration)

Synonym: Guanidinium rhodanide; Guanidinium thiocyanate

CAS Number: 593-84-0
Empirical Formula (Hill Notation): CH5N3 · CHNS
Molecular Weight: 118.16
EC Number: 209-812-1
MDL Number: MFCD00013027
Linear Formula: NH2C(=NH)NH2 · HSCN
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-G6639-25G 25 g
$40.30
1/EA
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45-G6639-100G 100 g
$118.00
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45-G6639-250G 250 g
$262.00
1/EA
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45-G6639-500G 500 g
$466.00
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45-G6639-1KG 1 kg
$782.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: G6639-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G6639-1KG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: G6639-250G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: G6639-500G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: G6639-1KG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: G6639-25G

 

anion traces chloride (Cl-): ≤2.5%
assay ≥97% (titration)
biological source synthetic
color white to off-white
form powder or crystals
InChI 1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H
InChI key ZJYYHGLJYGJLLN-UHFFFAOYSA-N
mp 120-122 °C (lit.)
Quality Level 200 
SMILES string SC#N.NC(N)=N
solubility water: 4 M, clear, colorless
technique(s) RNA extraction: suitable
Application: Chaotropic agent and strong denaturant; solubilizes cells.
Application: Guanidine thiocyanate has been used:
• as a denaturing agent to study its effects on surface activity of globular protein
• for the extraction of total RNA from primary hepatocytes
• as a component of the incubating buffer for extraction of DNA from human bone
• as a component of the guanidine thiocyanate (GITC) lysis buffer for extraction of elephant shark DNA
• as a component of lysis solution for extraction of RNA from rat pancreatic tissues
Biochem/physiol Actions: Guanidine thiocyanate (GTC) is a powerful protein denaturant and can denature endogenous ribonucleases. It plays a role in separation of ribosomal ribonucleic acid (rRNA) from ribosomes. GTC in combination with phenol and chloroform can be used in isolation of total RNA from cells and tissues.
Packaging: 1 kg in glass bottle
Packaging: 25, 100, 250 g in poly bottle
Packaging: 500 g in glass bottle
Purity ≥97% (titration)
mp 120-122 °C (lit.)
UNSPSC 12352209

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