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Iodoacetic acid

SIAL/I4386 - ≥98.0% (T)

Synonym: 2-Iodoacetic acid

CAS Number: 64-69-7
Empirical Formula (Hill Notation): C2H3IO2
Molecular Weight: 185.95
EC Number: 200-590-1
MDL Number: MFCD00002685
Linear Formula: ICH2CO2H
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-I4386-10G 10 g
 $59.40
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45-I4386-25G 25 g
 $110.00
1/EA		 Add To Favorites
45-I4386-100G 100 g
 $334.00
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assay ≥98.0% (T)
biological source synthetic
color white to yellow
form powder or flakes
InChI 1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5)
InChI key JDNTWHVOXJZDSN-UHFFFAOYSA-N
mp 77-79 °C (lit.)
Quality Level 200 
SMILES string OC(=O)CI
solubility H2O: soluble, clear to hazy
storage temp. −20°C
Application: Iodoacetic acid has been used as an alkylating agent for antibody AR37, serum proteins and strawberry proteome samples extracted from different stages of ripened fruit.
Application: Reagent for the modification of cysteine residues in proteins.
Biochem/physiol Actions: Iodoacetic acid (IAA) blocks the thiol group of cysteine. IAA inhibits glyceraldehyde-3-phosphate dehydrogenase (G3PDH) by interacting with sulfhydryl group of the active site cysteine. IAA inhibits the progression of solid Ehrlich carcinoma. IAA is one of the iodinated disinfection byproducts in drinking water. It is cytotoxic to mammalian cells.
Packaging: 10, 25, 100 g in glass bottle
Purity ≥98.0% (T)
mp 77-79 °C (lit.)
Storage Temp. −20°C
UNSPSC 12352106

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