Iodoacetic acid

SIAL/I4386 - ≥98.0% (T)

Synonym: 2-Iodoacetic acid

CAS Number: 64-69-7
Empirical Formula (Hill Notation): C₂H₃IO₂
Molecular Weight: 185.95
EC Number: 200-590-1
MDL Number: MFCD00002685
Linear Formula: ICH₂CO₂H
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-I4386-10G	10 g	$55.60 1/EA		Add To Favorites
45-I4386-25G	25 g	$102.00 1/EA		Add To Favorites
45-I4386-100G	100 g	$312.00 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	≥98.0% (T)
biological source	synthetic
color	white to yellow
form	powder or flakes
InChI	1S/C2H3IO2/c3-1-2(4)5/h1H2,(H,4,5)
InChI key	JDNTWHVOXJZDSN-UHFFFAOYSA-N
mp	77-79 °C (lit.)
Quality Level	200
SMILES string	OC(=O)CI
solubility	H₂O: soluble, clear to hazy
storage temp.	−20°C

Application:	Iodoacetic acid has been used as an alkylating agent for antibody AR37, serum proteins and strawberry proteome samples extracted from different stages of ripened fruit.
Application:	Reagent for the modification of cysteine residues in proteins.
Biochem/physiol Actions:	Iodoacetic acid (IAA) blocks the thiol group of cysteine. IAA inhibits glyceraldehyde-3-phosphate dehydrogenase (G3PDH) by interacting with sulfhydryl group of the active site cysteine. IAA inhibits the progression of solid Ehrlich carcinoma. IAA is one of the iodinated disinfection byproducts in drinking water. It is cytotoxic to mammalian cells.
Packaging:	10, 25, 100 g in glass bottle

Symbol	GHS05,GHS06
Signal word	Danger
Hazard statements	H301 - H314
Precautionary statements	P260 - P280 - P301 + P310 + P330 - P303 + P361 + P353 - P305 + P351 + P338 + P310
Hazard Codes	T,C
Risk Statements	25-35
Safety Statements	22-36/37/39-45
RIDADR	UN 2923 6.1(8) / PGI
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥98.0% (T)
mp	77-79 °C (lit.)
Storage Temp.	−20°C
UNSPSC	12352106

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