Lomustine
SIAL/L0745000 - European Pharmacopoeia (EP) Reference Standard
Synonym: 1-
CAS Number: 13010-47-4
Empirical Formula (Hill Notation): C9H16ClN3O2
Molecular Weight: 233.70
MDL Number: MFCD00012392
Linear Formula: C9H16ClN3O2
Product Type: Chemical
| API family | lomustine |
| application(s) | pharmaceutical (small molecule) |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C9H16ClN3O2/c10-6-7-13 |
| InChI key | GQYIWUVLTXOXAJ-UHFFFAOYSA |
| manufacturer/tradename | EDQM |
| SMILES string | ClCCN(N=O)C(=O)NC1CCCCC1 |
| storage temp. | 2-8°C |
| Application: | Lomustine EP Reference standard, intended for use in laboratory tests only as specifically prescribed in the European Pharmacopoeia. |
| Biochem/physiol Actions: | Antineoplastic agent with cellular DNA effects. Lomustine induces p53 expression in A2870 cells. |
| General description: | Nitrosamines are chemical compounds that can form during drug manufacturing and may pose health risks, including carcinogenicity. This product is provided as delivered and specified by the issuing Pharmacopoeia. For further information and support, including certificate/ product information sheets, please go to the website of the issuing Pharmacopoeia   . |
| Other Notes: | Sales restrictions may apply. |
| Packaging: | The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
| Symbol |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H301 - H350 |
| Precautionary statements | P201 - P301 + P310 + P330 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |