Sodium dodecyl sulfate
SIAL/L4509 - ReagentPlus®, ≥98.5% (GC)
Synonym: Dodecyl sodium sulfate; Dodecyl sulfate sodium salt; Lauryl sulfate sodium salt; SDS; Sodium lauryl sulfate
CAS Number: 151-21-3
Empirical Formula (Hill Notation): C12H25NaO4S
Molecular Weight: 288.38
EC Number: 205-788-1
MDL Number: MFCD00036175
Linear Formula: CH3(CH2)11OSO3Na
Product Type: Chemical
aggregation number | 62 |
assay | ≥98.5% (GC) |
biological source | synthetic |
cation traces | Na: 7.0-9.0% |
CMC | 7-10 mM (20-25°C) |
density | 0.425 g/cm3 |
description | anionic |
form | powder |
HLB | 40 |
impurities | <2.0% water (Karl Fischer) |
InChI | 1S/C12H26O4S.Na/c1-2-3-4- |
InChI key | DBMJMQXJHONAFJ-UHFFFAOYSA |
mol wt | micellar avg mol wt 18,000 |
mp | 204-207 °C (lit.) |
product line | ReagentPlus® |
Quality Level | 200 |
SMILES string | [Na+].CCCCCCCCCCCCOS([O-] |
solubility | water: soluble |
transition temp | cloud point >100 °C |
Application: | Anionic detergent |
Application: | Sodium dodecyl sulphate (SDS) has been used: • in the characterization of Enterobacteriaceae strain based on sensitivity to selective compounds • to treat human skin in vitro and in vivo to evaluate the role of nuclear localization of 27-kDa heat shock protein (HSP27) in potential skin irritation • in the decellularization of porcine heart valve tissue • to treat sperm for in vitro induction of sperm decondensation |
Biochem/physiol Actions: | Sodium dodecyl sulphate (SDS) helps to quickly disrupt the biological membranes. It is usually used as one of the major constituent of several reagents, that are used to purify nucleic acids. SDS can block the activity of RNase and deoxyribonuclease (DNase). |
Features and Benefits: | • Suitable for Cell Biology and Biochemical Research • High purity chemical suitable for multiple research applications |
General description: | Sodium dodecyl sulfate (SDS), or sodium lauryl sulfate, is widely recognized as an anionic surfactant within the organosulfate class of organic compounds. Its effectiveness as a detergent spans both ionic and anionic conditions. SDS plays a critical role as a protein denaturant, facilitating the solubilization and denaturation of proteins in procedures like protein extraction and SDS-PAGE. Its significance in the electrophoretic separation of proteins and lipids establishes its indispensability for the examination of these molecules in diverse biological experiments. In conclusion, Sodium dodecyl sulfate proves to be an indispensable element in the exploration of biological molecules within the realms of biochemical and cell biology research. |
Legal Information: | ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany |
Other Notes: | 2024 CiteAb Award Winner for Supplier Succeeding in Parkinson′s Research |
Other Notes: | For additional information on our range of Biochemicals , please complete this form . |
Packaging: | 1 kg in poly drum |
Packaging: | 10, 25, 100, 250, 500 g in poly bottle |
Symbol | GHS02,GHS05,GHS07 |
Signal word | Danger |
Hazard statements | H228 - H302 + H332 - H315 - H318 - H335 - H412 |
Precautionary statements | P210 - P273 - P280 - P301 + P312 - P304 + P340 + P312 - P305 + P351 + P338 |
Hazard Codes | F,Xn |
Risk Statements | 11-21/22-37/38-41 |
Safety Statements | 26-36/37-39 |
RIDADR | UN1325 - class 4.1 - PG 3 - Flammable solids, organic, n.o.s., H |
WGK Germany | WGK 2 |
Flash Point(F) | 338.0 °F |
Flash Point(C) | 170 °C |
Purity | ≥98.5% (GC) |
mp | 204-207 °C (lit.) |
Density | 0.425 g/cm3 |
UNSPSC | 12161900 |