LightOx™26
SIAL/LIGHTOX26 - ≥95% (HPLC)
CAS Number: 2324144-72-9
Empirical Formula (Hill Notation): C23H27NO2
Molecular Weight: 349.47
Linear Formula: C23H27NO2
Product Type: Chemical
| assay | ≥95% (HPLC) |
| form | powder |
| storage temp. | 2-8°C |
| Application: | Fluorescence microscopy, fluorescent retinoid binding assay, fluorescence spectroscopy. |
| Biochem/physiol Actions: | Strong ligand for retinoic acid receptor proteins |
| Features and Benefits: | LightOx26 is a synthetic analogue of all-trans-retinoic acid (ATRA), that exhibits solvatochromatic fluorescence emission when excited with UV or 405 nm light. The compound is a strong ligand for the retinoic acid receptor proteins (RARs) and related cellular retinoic acid binding proteins (CRABPI/II) and can, therefore, be used as a replacement for ATRA in cellular assays involving retinoid signaling processes. LightOx26 can be utilised to study retinoid behaviour using fluorescence microscopy, employed in a competitive fluorometric ligand-binding assay for direct determination of the strength of binding of non-fluorescent retinoids to a protein target, and as a fluorophore in fluorescence spectroscopy. |
| Legal Information: | LightOx is a trademark of LightOx Ltd. |
| Other Notes: | Chemical Equivalency 1ea=1mg |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95% (HPLC) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352200 |