Sodium 2-mercaptoethanesulfonate
SIAL/M1511 - analytical standard, ≥98.0% (titration)
Synonym: 2-
CAS Number: 19767-45-4
Empirical Formula (Hill Notation): C2H5NaO3S2
Molecular Weight: 164.18
EC Number: 243-285-9
MDL Number: MFCD00007535
Linear Formula: HSCH2CH2SO3Na
Product Type: Chemical
| application(s) | clinical testing |
| assay | ≥98.0% (titration) |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C2H6O3S2.Na/c3-7(4,5)2 |
| InChI key | XOGTZOOQQBDUSI-UHFFFAOYSA |
| Quality Level | 200  |
| SMILES string | [Na+].[O-]S(=O)(=O)CCS |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | The analytical standard can also be used as follows:• Quantification of sodium 2-mercaptoethanesulfonate (MESNA) from human samples by micellar electrokinetic chromatography (MEKC) coupled with UV detection and in-capillary derivatization of MESNA • Development of a fluorescence-enhanced histidine stabilized gold nanoclusters (His-Au NCs) based probe for the detection of sodium 2-mercaptoethanesulfonate in uromitexan samples • High-performance liquid chromatography-tandem mass spectrometric based bioanalysis of sodium 2-mercaptoethanesulfonate in rat plasma samples • To quantify sodium 2-mercaptoethanesulfonate in two of its pharmaceutical preparations (injections) by surface-enhanced Raman scattering (SERS) using gold colloid as a probe |
| General description: | Sodium 2-mercaptoethanesulfonate is a thiol compound commonly used as an auxiliary drug, to reduce the side effects of anti-cancer drugs, such as oxazaphosphorine, cyclophosphamide, and ifosfamide. It acts by forming a non-toxic compound upon reacting with the toxic metabolites of the drugs like acrolein. |
| Other Notes: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Packaging: | 5, 10, 25 g in poly bottle |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.0% (titration) |
| UNSPSC | 41116107 |