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Sodium 2-mercaptoethanesulfonate

SIAL/M1511 - analytical standard, ≥98.0% (titration)

Synonym: 2-Mercaptoethanesulfonic acid sodium salt; Coenzyme M sodium salt; HS-CoM Na; MESNA

CAS Number: 19767-45-4
Empirical Formula (Hill Notation): C2H5NaO3S2
Molecular Weight: 164.18
EC Number: 243-285-9
MDL Number: MFCD00007535
Linear Formula: HSCH2CH2SO3Na
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-M1511-5G 5 g
$79.20
1/EA
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45-M1511-10G 10 g
$132.00
1/EA
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45-M1511-25G 25 g
$264.00
1/EA
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application(s) clinical testing
assay ≥98.0% (titration)
format neat
grade analytical standard
InChI 1S/C2H6O3S2.Na/c3-7(4,5)2-1-6;/h6H,1-2H2,(H,3,4,5);/q;+1/p-1
InChI key XOGTZOOQQBDUSI-UHFFFAOYSA-M
Quality Level 200 
SMILES string [Na+].[O-]S(=O)(=O)CCS
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Application: The analytical standard can also be used as follows:• Quantification of sodium 2-mercaptoethanesulfonate (MESNA) from human samples by micellar electrokinetic chromatography (MEKC) coupled with UV detection and in-capillary derivatization of MESNA
• Development of a fluorescence-enhanced histidine stabilized gold nanoclusters (His-Au NCs) based probe for the detection of sodium 2-mercaptoethanesulfonate in uromitexan samples
• High-performance liquid chromatography-tandem mass spectrometric based bioanalysis of sodium 2-mercaptoethanesulfonate in rat plasma samples
• To quantify sodium 2-mercaptoethanesulfonate in two of its pharmaceutical preparations (injections) by surface-enhanced Raman scattering (SERS) using gold colloid as a probe
General description: Sodium 2-mercaptoethanesulfonate is a thiol compound commonly used as an auxiliary drug, to reduce the side effects of anti-cancer drugs, such as oxazaphosphorine, cyclophosphamide, and ifosfamide. It acts by forming a non-toxic compound upon reacting with the toxic metabolites of the drugs like acrolein.
Other Notes: Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Packaging: 5, 10, 25 g in poly bottle
Hazard Codes Xi
Risk Statements 36/37/38
Safety Statements 26-36
RIDADR NONH for all modes of transport
WGK Germany WGK 2
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥98.0% (titration)
UNSPSC 41116107

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