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8-Methoxypsoralen

SIAL/M3501 - analytical standard

Synonym: 8-MOP; 9-Methoxyfuro[3,2-g][1]benzopyran-7-one; Ammoidin; Methoxsalen; Xanthotoxin

CAS Number: 298-81-7
Empirical Formula (Hill Notation): C12H8O4
Molecular Weight: 216.19
EC Number: 206-066-9
MDL Number: MFCD00005009
Linear Formula: C12H8O4
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-M3501-1G 1 g
 $57.40
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45-M3501-5G 5 g
 $274.00
1/EA		 Add To Favorites
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: M3501-1G

 

application(s) food and beverages
color white to yellow
form crystals
  fibers
  powder
format neat
grade analytical standard
InChI 1S/C12H8O4/c1-14-12-10-8(4-5-15-10)6-7-2-3-9(13)16-11(7)12/h2-6H,1H3
InChI key QXKHYNVANLEOEG-UHFFFAOYSA-N
mp 148-150 °C (lit.)
Quality Level 100 
SMILES string COc1c2OC(=O)C=Cc2cc3ccoc13
solubility acetic acid: soluble
  H2O: slightly soluble
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Application: Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.
Biochem/physiol Actions: 8-methoxypsoralen (8-MOP) plus ultraviolet A (UVA) irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms. Cultured normal human melanocytes treated with 8-methoxypsoralen and irradiated with ultraviolet A (UVA) formed 8-methoxypsoralen-phospholipid photoadducts that could be substituted for diacylglycerol to activate protein kinase C in a cell-free system. 8-MOP is an inactivator of purified reconstituted cytochrome P450. It also inhibits substance P-induced histamine release from substance P-activated rat peritoneal mast cells by suppressing the rise in [Ca2+].
Disclaimer: Protect from light.
Packaging: 1, 5 g in glass bottle
mp 148-150 °C (lit.)
UNSPSC 41116107

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