Metronidazole
SIAL/M3761 - analytical standard
Synonym: 2-
CAS Number: 443-48-1
Empirical Formula (Hill Notation): C6H9N3O3
Molecular Weight: 171.15
EC Number: 207-136-1
MDL Number: MFCD00009750
Linear Formula: C6H9N3O3
Product Type: Chemical
| antibiotic activity spectrum | Gram-negative bacteria |
| parasites | |
| application(s) | forensics and toxicology pharmaceutical (small molecule) |
| form | crystalline |
| format | neat |
| grade | analytical standard |
| InChI | 1S/C6H9N3O3/c1-5-7-4-6(9( |
| InChI key | VAOCPAMSLUNLGC-UHFFFAOYSA |
| mode of action | DNA synthesis | interferes |
| mp | 159-161 °C (lit.) |
| Quality Level | 100  |
| SMILES string | CC1=NC=C([N+]([O-])=O)N1C |
| storage temp. | 2-8°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Application: | The analytical standard can be used as follows:• Cyclic voltametric determination of metronidazole at carbon paste electrode (CPE) in three different brands of metronidazole tablets • Simultaneous determination of metronidazole, diloxanide, spiramycin, and cliquinol in pharmaceutical dosage forms by reversed-phase high-performance liquid chromatography coupled to photodiode array detector (RP-HPLC-DAD) • Development of an electrochemical sensor based on polydopamine/carboxylic multi-walled carbon nano-tubes (MWCNTs-COOH) nanocomposites for the determination of metronidazole • Liquid chromatography–ion trap mass spectrometry (LC-MS/MS based analysis of metronidazole in water, sediment, and fish tissue samples • Determination of metronidazole using an electrochemical sensor based on multi-walled carbon nanotubes (MWCNTs) and chitosan-nickel complexes (CTS-Ni) in tablets, human urine, and serum samples |
| General description: | Metronidazole is a nitroimidazole drug, used particularly against infections caused by anaerobic bacteria and protozoa in humans and domestic animals. |
| Other Notes: | Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support. |
| Packaging: | 5, 25, 100 g in poly bottle |
| Symbol |  GHS08 |
| Signal word | Danger |
| Hazard statements | H340 - H350 - H373 |
| Precautionary statements | P201 - P202 - P260 - P280 - P308 + P313 - P405 |
| Hazard Codes | Xn |
| Risk Statements | 40 |
| Safety Statements | 36/37 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| mp | 159-161 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |