Nicotinamide
SIAL/N0600000 - European Pharmacopoeia (EP) Reference Standard
Synonym: Niacinamide; Nicotinic acid amide; Pyridine-
CAS Number: 98-92-0
Empirical Formula (Hill Notation): C6H6N2O
Molecular Weight: 122.12
MDL Number: MFCD00006395
Linear Formula: C6H6N2O
Product Type: Chemical
| API family | nicotinamide |
| application(s) | pharmaceutical (small molecule) |
| biological source | synthetic |
| form | solid |
| format | neat |
| grade | pharmaceutical primary standard |
| InChI | 1S/C6H6N2O/c7-6(9)5-2-1-3 |
| InChI key | DFPAKSUCGFBDDF-UHFFFAOYSA |
| manufacturer/tradename | EDQM |
| mp | 128-131 °C (lit.) |
| SMILES string | NC(=O)c1cccnc1 |
| storage temp. | 2-8°C |
| technique(s) | gas chromatography (GC): suitable |
| liquid chromatography (LC): suitable |
| Application: | Nicotinamide can be used as an EP reference standard for the quantification of the analyte in pharmaceutical formulations and biological fluids by chromatography, UV-visible spectrophotometry and multivariate analysis. |
| Biochem/physiol Actions: | Nicotinamide is an amide derivative of vitamin B3 and a PARP inhibitor |
| General description: | This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the Issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia   .Nicotinamide belongs to the group of water-soluble B vitamins. It is generally formed from nicotinic acid (vitamin B3). It is available in food products and is utilized for the treatment of pellagra, psoriasis, schizophrenia, and type I diabetes. It is also known for its anti-inflammatory activity. |
| Other Notes: | Sales restrictions may apply. |
| Packaging: | The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue . |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P305 + P351 + P338 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 359.6 °F |
| Flash Point(C) | 182 °C |
| mp | 128-131 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |