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β-Nicotinamide adenine dinucleotide hydrate

SIAL/N1636 - purified by column chromatography, ≥99%

Synonym: β-DPN; β-NAD; Coenzyme 1; Cozymase; DPN; Diphosphopyridine nucleotide; NAD; Nadide

CAS Number: 53-84-9
Empirical Formula (Hill Notation): C21H27N7O14P2 · xH2O
Molecular Weight: 663.43 (anhydrous basis)
EC Number: 200-184-4
MDL Number: MFCD00036253
Linear Formula: C21H27N7O14P2 · xH2O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-N1636-25MG 25 mg
$51.40
1/EA
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45-N1636-100MG 100 mg
$120.00
1/EA
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45-N1636-250MG 250 mg
$204.00
1/EA
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45-N1636-1G 1 g
$614.00
1/EA
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: N1636-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: N1636-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.

This image depicts SKU: N1636-250MG

 

assay ≥99%
color white
form crystalline powder
InChI 1S/C21H27N7O14P2/c22-17-12-19(25-7-24-17)28(8-26-12)21-16(32)14(30)11(41-21)6-39-44(36,37)42-43(34,35)38-5-10-13(29)15(31)20(40-10)27-3-1-2-9(4-27)18(23)33/h1-4,7-8,10-11,13-16,20-21,29-32H,5-6H2,(H5-,22,23,24,25,33,34,35,36,37)/t10-,11-,13-,14-,15-,16-,20-,21-/m1/s1
InChI key BAWFJGJZGIEFAR-NNYOXOHSSA-N
Quality Level 200 
SMILES string NC1=NC=NC2=C1N=CN2.O[C@@H]3[C@@H](COP(O)(OP(OC[C@@H](O4)[C@@H](O)[C@@H](O)[C@H]4[N+]5=CC=CC(C(N)=O)=C5)([O-])=O)=O)OC[C@@H]3O
storage temp. −20°C
Application: β-Nicotinamide adenine dinucleotide hydrate has been used:
• to measure adenosine triphosphate (ATP) synthesis rates (kinetics measurements)
• in the reaction buffer for pyruvate kinase (PK) activity assay
• as a component of master mix for a high throughput screening

Biochem/physiol Actions: Electron acceptor
Biochem/physiol Actions: β-Nicotinamide adenine dinucleotide (NAD) cycles between the oxidized (NAD+) and reduced (NADH) forms to maintain a redox balance necessary for continued cell growth. It significantly participates in enzyme-catalyzed oxido-reduction processes and many genetic processes. It is also involved in microbial catabolism.
General description: β-Nicotinamide adenine dinucleotide (NAD) is an electron carrier and a cofactor. It is ubiquitously found in the living system. NAD+ contains an adenylic acid and a nicotinamide-5′-ribonucleotide group linked together by a pyrophosphate moiety. In NAD+ complexes, the enzyme-cofactor interactions are highly conserved.
Other Notes: Crystalline NAD contains less than 0.1% (w/w) residual organic solvent, is less hygroscopic and electrostatic, and is more stable at ambient temperatures than amorphous NAD.
Other Notes: This is the common form of NAD.
Packaging: 1 g in poly bottle
Packaging: 25, 100, 250 mg in poly bottle
Packaging: Packaged by solid weight.
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99%
Storage Temp. −20°C
UNSPSC 12352200

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