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Nicotinic acid

SIAL/N5410 - meets USP testing specifications

Synonym: 3-Picolinic acid; Niacin; Pellagra preventive factor; Pyridine-3-carboxylic acid; Vitamin B3

CAS Number: 59-67-6
Empirical Formula (Hill Notation): C6H5NO2
Molecular Weight: 123.11
EC Number: 200-441-0
MDL Number: MFCD00006391
Linear Formula: C6H5NO2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-N5410-100G 100 g
 $408.00
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This image depicts SKU: N5410-100G

 

agency meets USP testing specifications
  USP/NF
application(s) pharmaceutical (small molecule)
assay 99.0-101.0% dry basis
biological source synthetic (organic)
color white
form powder
InChI 1S/C6H5NO2/c8-6(9)5-2-1-3-7-4-5/h1-4H,(H,8,9)
InChI key PVNIIMVLHYAWGP-UHFFFAOYSA-N
mp 236-239 °C (lit.)
Quality Level 200 
SMILES string OC(=O)c1cccnc1
Application: Nicotinic acid has been used as an antioxidant to evaluate its protective functionality in colon LoVo cell lines against doxorubicin induced cytotoxicity.
Biochem/physiol Actions: Nicotinic modulates lipid metabolism and may be useful in treating dyslipidemia. It is an antioxidant and acts as a coenzyme in the form of nicotinamide adenine nucleotides. Deficiency of niacin leads to enhanced lipid peroxidation and is also implicated in Crohn′s disease Deficiency also impacts DNA repair and also leads to skin and gastrointestinal disorder, pellagra. Nicotinic acid reduces the low-density lipoprotein (LDL) synthesis and improves high-density lipoprotein (HDL) levels.
General description: Nicotinic acid, also referred to as niacin or as vitamin B3, is a water-soluble vitamin. Nicotinic acid is synthesized from the amino acid tryptophan and is present majorly in peanuts, fish and lean meat.
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H319
Precautionary statements P280 - P305 + P351 + P338 - P337 + P313
Hazard Codes Xi
Risk Statements 36
Safety Statements 26
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) 379.4 °F - closed cup
Flash Point(C) 193 °C - closed cup
Purity 99.0-101.0% dry basis
mp 236-239 °C (lit.)
UNSPSC 12352106

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