Novobiocin sodium
SIAL/N6160 - meets USP testing specifications
Synonym: Novobiocin sodium salt
CAS Number: 1476-53-5
Empirical Formula (Hill Notation): C31H35N2NaO11
Molecular Weight: 634.61
EC Number: 216-023-6
Linear Formula: C31H35N2NaO11
Product Type: Chemical
agency | meets USP testing specifications |
USP/NF | |
antibiotic activity spectrum | Gram-positive bacteria |
application(s) | pharmaceutical (small molecule) |
form | powder |
InChI | 1S/C31H35N2O11.Na/c1-14(2 |
InChI key | AXOUUAINTJNFRS-UHFFFAOYSA |
mode of action | DNA synthesis | interferes |
enzyme | inhibits | |
Quality Level | 200 |
SMILES string | [Na+].CO[C@@H]1[C@@H](OC( |
storage temp. | 2-8°C |
Application: | For the production of positively supercoiled plasmid DNA. Inhibitor of bacterial DNA gyrase and eukaryotic DNA topoisomerase. Inhibitor of retrovirus RNA-dependent DNA-polymerase. |
Biochem/physiol Actions: | Mode of Action: Inhibits DNA synthesis by inhibiting the enzyme Topoisomerase II. Antimicrobial spectrum: Gram-positive bacterial. |
General description: | Chemical structure: coumarin-glycoside |
Other Notes: | Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place |
Packaging: | 1, 5, 25 g in glass bottle |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H302 - H317 - H319 |
Precautionary statements | P261 - P264 - P280 - P301 + P312 - P302 + P352 - P305 + P351 + P338 |
Hazard Codes | Xi |
Risk Statements | 36-43 |
Safety Statements | 26-36/37 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-8°C |
UNSPSC | 51101500 |