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Pefloxacin mesilate dihydrate

SIAL/P0309000 - European Pharmacopoeia (EP) Reference Standard

Synonym: Pefloxacin mesylate dihydrate; 3-Quinolinecarboxylic acid, 1-ethyl-6-fluoro-1,4-dihydro-7-(4-methyl-1-piperazinyl)-4-oxo-, monomethanesulfonate, dihydrate; Pefloxacine monomethanesulfonate dihydrate; Pefloxacinium methanesulfonate dihydrate

CAS Number: 149676-40-4
Empirical Formula (Hill Notation): C18H28FN3O8S
Molecular Weight: 465.49
MDL Number: MFCD01685696
Linear Formula: C17H20FN3O3 • CH4O3S • 2H2O
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-P0309000
$153.00
1/EA		 Add To Favorites

 

application(s) pharmaceutical (small molecule)
format neat
grade pharmaceutical primary standard
InChI 1S/C17H20FN3O3.CH4O3S.2H2O/c1-3-20-10-12(17(23)24)16(22)11-8-13(18)15(9-14(11)20)21-6-4-19(2)5-7-21;1-5(2,3)4;;/h8-10H,3-7H2,1-2H3,(H,23,24);1H3,(H,2,3,4);2*1H2
InChI key LEULAXMUNMRLPW-UHFFFAOYSA-N
manufacturer/tradename EDQM
SMILES string O.O.CS(O)(=O)=O.CCN1C=C(C(O)=O)C(=O)c2cc(F)c(cc12)N3CCN(C)CC3
storage temp. 2-8°C
Biochem/physiol Actions: Pefloxacin inhibits the bacterial enzymes DNA gyrase and topoisomerase IV, which are needed for the transcription and replication of bacterial DNA. DNA gyrase is thought to be the primary quinolone target for gram-negative bacteria. Topoisomerase IV is thought to be the primary target in gram-positive organisms. The inhibition of the topoisomerases results in strand breakage of the bacterial chromosome, supercoiling, and resealing. Therefore, DNA replication and transcription is inhibited . Pefloxacin is an analog of norfloxacin.
Caution: Please find SDS provided by EDQM here. .
General description: This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia.For further information and support please go to the website of the issuing Pharmacopoeia .
Other Notes: Sales restrictions may apply.
Packaging: Unit quantity: 200 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity, please visit the EDQM reference substance catalogue .
Storage Temp. 2-8°C
UNSPSC 41116107

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