TWEEN® 80
SIAL/P1754 - viscous liquid
Synonym: POE (20) sorbitan monooleate; Polyethylene glycol sorbitan monooleate; Polyoxyethylenesorbitan monooleate; Polysorbate 80
CAS Number: 9005-65-6
MDL Number: MFCD00082107
Product Type: Chemical
aggregation number | 60 |
application(s) | cell analysis |
CMC | 0.012 mM (20-25°C) |
composition | Oleic acid, ≥58.0% (balance primarily linoleic, palmitic, and stearic acids) |
density | 1.064 g/cm3 |
description | non-ionic |
form | viscous liquid |
HLB | 15 |
InChI | 1S/C32H60O10/c1-2-3-4-5-6 |
InChI key | RGPBUVUVZKQNHD-MDZDMXLPSA |
mol wt | average mol wt 1310 |
micellar avg mol wt 79,000 | |
Quality Level | 200 ![]() |
transition temp | cloud point 65 °C |
Application: | Non-ionic detergent used for selective protein extraction and isolation of nuclei from mammalian cell lines. |
Application: | TWEEN® 80 has been used in drug vehicle solution for specific injections in mice and rats. It has been used for the determination of esterase activity in bacterial cells. |
Biochem/physiol Actions: | TWEEN® 80 is a polysorbate surfactant which helps in stabilizing proteins and in protein membrane studies. It is regularly used for the extraction of membrane proteins and isolation of nuclei from cells. |
Legal Information: | TWEEN is a registered trademark of Croda International PLC |
Packaging: | 1 gal in poly bottle |
Packaging: | 1 L in poly bottle |
Packaging: | 25, 500 mL in poly bottle |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | 235.4 °F - closed cup |
Flash Point(C) | > 113 °C - closed cup |
Density | 1.064 g/cm3 |
UNSPSC | 12161900 |