Penicillin G potassium salt
SIAL/P8721
Synonym: Benzylpenicillin potassium salt
CAS Number: 113-98-4
Empirical Formula (Hill Notation): C16H17KN2O4S
Molecular Weight: 372.48
EC Number: 204-038-0
MDL Number: MFCD00036193
Linear Formula: C16H17KN2O4S
Product Type: Chemical
antibiotic activity spectrum | Gram-positive bacteria |
application(s) | pharmaceutical (small molecule) |
form | crystalline powder |
InChI | 1S/C16H18N2O4S.K/c1-16(2) |
InChI key | IYNDLOXRXUOGIU-LQDWTQKMSA |
mode of action | cell wall synthesis | interferes |
potency | 1440-1680 units per mg |
Quality Level | 200 |
SMILES string | [K+].[H][C@]12SC(C)(C)[C@ |
solubility | H2O: 100 mg/mL |
Application: | Penicillin G is a narrow spectrum antibiotic derived from Streptococcus pneumoniae. It is the drug of choice for groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridians group streptococci, and non-penicillinase producing staphylococcus. The potassium salt has been used to study murosomes of staphylococci and the penicillin-induced lysis of Streptococcus mutans. |
Biochem/physiol Actions: | Mode of Action: Penicillin G acts by inhibiting cell wall synthesis through binding to penicillin binding proteins (PBPs), inhibiting peptidoglycan chain cross-linking. Antimicrobial spectrum: This product is active against gram-positive and gram-negative bacteria. |
Caution: | Solutions should be filter sterilized and stored at 2-8°C for 1 week or at -20°C for more lengthy periods. Solutions are stable at 37°C for 3 days. The sodium salt is soluble in H2O at 100 mg/mL. |
General description: | Chemical structure: ß-lactam |
Other Notes: | Keep container tightly closed in a dry and well-ventilated place.Keep in a dry place |
Packaging: | 10mu,25mu,100mu |
Symbol | GHS07 |
Signal word | Warning |
Hazard statements | H317 |
Precautionary statements | P280 - P302 + P352 |
Hazard Codes | Xn |
Risk Statements | 42/43 |
Safety Statements | 36/37 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
UNSPSC | 51283405 |