1,10-Phenanthroline monohydrate
SIAL/P9375 - reagent grade
Synonym: o-Phenanthroline monohydrate
CAS Number: 5144-89-8
Empirical Formula (Hill Notation): C12H8N2 · H2O
Molecular Weight: 198.22
EC Number: 200-629-2
MDL Number: MFCD00149973
Linear Formula: C12H8N2 · H2O
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P9375-100G
This image depicts SKU: P9375-100G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P9375-25G
This image depicts SKU: P9375-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P9375-1G
This image depicts SKU: P9375-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material.
This image depicts SKU: P9375-5G
This image depicts SKU: P9375-5G
| biological source | synthetic (organic) |
| form | powder |
| grade | reagent grade |
| InChI | 1S/C12H8N2.H2O/c1-3-9-5-6 |
| InChI key | PPQJCISYYXZCAE-UHFFFAOYSA |
| mp | 100-104 °C (lit.) |
| Quality Level | 200  |
| SMILES string | O.c1cnc2c(c1)ccc3cccnc23 |
| solubility | methanol: 200 mM (Stock solution is stable for months at –20° C.) |
| Application: | 1,10-Phenanthroline monohydrate has been used: • as an inhibitor of metalloproteinase (MMP) in MDA-MB-231 breast cancer cells • as a negative control in in situ zymography of mice heart samples • in in vitro resveratrol chelation and reducing activities assays to chelate iron |
| Application: | When complexed with copper, it possesses nuclease activity that has been used to study DNA-protein interactions. |
| Biochem/physiol Actions: | Metalloprotease inhibitor; chelates iron, zinc and other divalent metals. Effective concentration 1-10 mM. |
| General description: | Phenanthroline is a heterocyclic organic compound, which forms complexes with metal ions. These complexes have wide applications in biochemistry, catalysis and analytical chemistry. It complexes with iron and is exploited as a redox indicator. |
| Packaging: | 1, 5, 25, 100 g in poly bottle |
| Symbol |   GHS06,GHS09 |
| Signal word | Danger |
| Hazard statements | H301 - H410 |
| Precautionary statements | P264 - P270 - P273 - P301 + P310 - P391 - P405 |
| Hazard Codes | T,N |
| Risk Statements | 25-50/53 |
| Safety Statements | 45-60-61 |
| RIDADR | UN2811 - class 6.1 - PG 3 - EHS - Toxic solids, organic, n.o.s., |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 100-104 °C (lit.) |
| UNSPSC | 12352200 |