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Cucurbitacin E

SIAL/PHL80013 - phyproof® Reference Substance

Synonym: α-Elaterin; α-Elaterine

CAS Number: 18444-66-1
Empirical Formula (Hill Notation): C32H44O8
Molecular Weight: 556.69
Linear Formula: C32H44O8
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-PHL80013-10MG 10 mg
 $337.00
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application(s) food and beverages
assay ≥95.0% (HPLC)
format neat
grade primary reference standard
InChI 1S/C32H44O8/c1-17(33)40-27(2,3)13-12-23(36)32(9,39)25-21(35)15-29(6)22-11-10-18-19(14-20(34)26(38)28(18,4)5)31(22,8)24(37)16-30(25,29)7/h10,12-14,19,21-22,25,34-35,39H,11,15-16H2,1-9H3/b13-12+/t19-,21-,22+,25+,29+,30-,31+,32+/m1/s1
InChI key NDYMQXYDSVBNLL-MUYMLXPFSA-N
manufacturer/tradename PhytoLab
product line phyproof® Reference Substance
storage temp. 2-8°C
Biochem/physiol Actions: Cucurbitacin E is a potent inhibitor of actin depolymerization.
Biochem/physiol Actions: Cucurbitacin E is a potent inhibitor of actin depolymerization. Cucurbitacin E is more active than jasplakinolide, and has a different mechanism of action, binding to a different site. Cucurbitacin E binds specifically to filamentous actin (F-actin) forming a covalent bond at residue Cys257, but not to monomeric actin (G-actin), stabilizing F-actin, without affecting actin polymerization or nucleation.
General description: This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG.
Legal Information: phyproof is a registered trademark of PhytoLab GmbH & Co. KG
Symbol GHS07  GHS07
Signal word Warning
Hazard statements H302
Precautionary statements P301 + P312 + P330
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95.0% (HPLC)
Storage Temp. 2-8°C
UNSPSC 41116107

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