Cardamomin
SIAL/PHL80379 - phyproof® Reference Substance
Synonym: Cardamonin; (2E)
CAS Number: 19309-14-9
Empirical Formula (Hill Notation): C16H14O4
Molecular Weight: 270.28
MDL Number: MFCD00238554
Linear Formula: C16H14O4
Product Type: Chemical
assay | ≥98.0% (HPLC) |
format | neat |
grade | primary reference standard |
InChI | 1S/C16H14O4/c1-20-15-10-1 |
InChI key | NYSZJNUIVUBQMM-BQYQJAHWSA |
manufacturer/tradename | PhytoLab |
product line | phyproof® Reference Substance |
SMILES string | O=C(/C=C/C1=CC=CC=C1)C2=C |
storage temp. | 2-8°C |
Biochem/physiol Actions: | Cardamonin is a calchone from Aplinia species (zingiberaceous plant species). Cardamonin inhibits pigmentation in melanocytes through suppression of Wnt/b-catenin signaling pathway. Cardamonin suppressed Wnt/b-catenin signaling by a mechanism involving proteasome-mediated degradation of b-catenin (GSK-3b-independent pathway). Research has shown that Cardamonin possesses anti-inflammatory activity via suppression of NF-kB nuclear translocation and Ik-Ba phosphorylation. |
General description: | This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG |
Legal Information: | phyproof is a registered trademark of PhytoLab GmbH & Co. KG |
Symbol | ![]() |
Signal word | Warning |
Hazard statements | H302 |
Precautionary statements | P264 - P270 - P301 + P312 + P330 - P501 |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥98.0% (HPLC) |
Storage Temp. | 2-8°C |
UNSPSC | 41116107 |