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Indirubin

SIAL/PHL89716 - phyproof® Reference Substance

Synonym: Coroupitine B; Indigo Red; Indigopurpurin

CAS Number: 479-41-4
Empirical Formula (Hill Notation): C16H10N2O2
Molecular Weight: 262.26
MDL Number: MFCD00221745
Linear Formula: C16H10N2O2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-PHL89716-10MG 10 mg
$430.00
1/EA
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application(s) food and beverages
assay ≥95.0% (HPLC)
format neat
grade primary reference standard
InChI 1S/C16H10N2O2/c19-15-10-6-2-4-8-12(10)17-14(15)13-9-5-1-3-7-11(9)18-16(13)20/h1-8,17H,(H,18,20)/b14-13+
InChI key CRDNMYFJWFXOCH-BUHFOSPRSA-N
manufacturer/tradename PhytoLab
product line phyproof® Reference Substance
storage temp. −20°C
Application:

  • Indirubin for leukemia treatment: Indirubin′s role as a kinase inhibitor positions it as a potential therapeutic in leukemia treatment. Its inhibition of cyclin-dependent kinases suggests utility in cell cycle regulation, which is pivotal in leukemia pathology. Research highlights its capabilities to modulate kinase activity, providing a pathway to targeted cancer therapies (Wang et al., 2024 ).

  • Indirubin in cancer research: As an anti-cancer agent, Indirubin demonstrates efficacy in vitro, particularly in inducing apoptosis in cancer cells. Its interaction with cellular signaling pathways enhances its potential as a therapeutic agent in various cancers, underlining its importance in oncological studies (Li et al., 2024 ).

  • Indirubin for neurodegenerative disease study: Exploring Indirubin′s effects on neurodegenerative diseases, recent studies focus on its neuroprotective properties through the regulation of kinase signaling pathways. This research underpins its therapeutic potential in diseases like Alzheimer′s and Parkinson′s, indicating its broad applicability in neurology (Li et al., 2024 ).

General description: This substance is a primary reference substance with assigned absolute purity (considering chromatographic purity, water, residual solvents, inorganic impurities). The exact value can be found on the certificate. Produced by PhytoLab GmbH & Co. KG
Legal Information: phyproof is a registered trademark of PhytoLab GmbH & Co. KG
RIDADR NONH for all modes of transport
WGK Germany WGK 1
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥95.0% (HPLC)
Storage Temp. −20°C
UNSPSC 41116107

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