Thiamine hydrochloride
SIAL/PHR1037 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Aneurine hydrochloride; Vitamin B1 hydrochloride
CAS Number: 67-03-8
Empirical Formula (Hill Notation): C12H17ClN4OS · HCl
Molecular Weight: 337.27
EC Number: 200-641-8
MDL Number: MFCD00012780
Linear Formula: C12H17ClN4OS · HCl
Product Type: Chemical
| agency | traceable to Ph. Eur. Y0000467 |
| traceable to USP 1656002 | |
| API family | thiamine |
| application(s) | food and beverages |
| CofA | current certificate can be downloaded |
| form | solid |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C12H17N4OS.2ClH/c1-8-1 |
| InChI key | DPJRMOMPQZCRJU-UHFFFAOYSA |
| mp | 250 °C (dec.) (lit.) |
| Quality Level | 300  |
| SMILES string | CC1=NC(N)=C(C[N+]2=CSC(CC |
| storage temp. | 2-8°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Application: | Thiamine hydrochloride may be used as a standard in the determination of thiamine hydrochloride in food samples using high performance liquid chromatographic system coupled with fluorescence detector (HPLC/fluorimetry). It may be used pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using high-performance liquid chromatography technique. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAB9939 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards |
| General description: | Thiamine hydrochloride belongs to the class of water soluble, B vitamins. It is present most commonly in food-stuffs either in free form or phosphorylated form. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Recommended products: | Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H319 |
| Precautionary statements | P264 - P280 - P305 + P351 + P338 - P337 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 250 °C (dec.) (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |