Ciprofloxacin HCl
SIAL/PHR1044 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Ciprofloxacin hydrochloride monohydrate
CAS Number: 86393-32-0
Empirical Formula (Hill Notation): C17H18FN3O3 · HCl · H2O
Molecular Weight: 385.82
MDL Number: MFCD00242856
Linear Formula: C17H18FN3O3 · HCl · H2O
Product Type: Chemical
| agency | traceable to BP 929 |
| traceable to Ph. Eur. C2190000 | |
| traceable to USP 1134335 | |
| API family | ciprofloxacin |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C17H18FN3O3.ClH.H2O/c1 |
| InChI key | ARPUHYJMCVWYCZ-UHFFFAOYSA |
| Quality Level | 300  |
| SMILES string | O.Cl.OC(=O)C1=CN(C2CC2)c3 |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Ciprofloxacin HCl has been used as a test compound in combination with the high-throughput nanowell antibiotic susceptibility testing device to validate its effectiveness as an antibacterial agent, thereby preventing the growth of bacteria. It may also be used as a standard in the determination of ciprofloxacin HCl in pharmaceutical preparations and serum samples using reversed-phase high performance liquid chromatography (RP-HPLC). |
| Application: | Ciprofloxacin HCl may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations and biological fluids by chromatography and chemiluminescence detection. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAB3671 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Ciprofloxacin HCl is a fluoroquinolone antibiotic agent, which shows a broad spectrum of antibacterial activity against gram positive and gram negative bacteria. |
| General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Ciprofloxacin is grouped under the class of second generation of quinolone analogs of nalidixic acid that exhibits high potency, minimal toxicity and a broad-spectrum antibacterial activity. It can be administered both parenterally and orally. It finds applications in the treatment of broad range of infections of the urinary tract, respiratory tract and gastrointestinal tract, as well as skin and soft tissue infections. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |