Mesalamine
SIAL/PHR1060 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 5-Aminosalicylic acid; 5-AS; 5-
CAS Number: 89-57-6
Empirical Formula (Hill Notation): C7H7NO3
Molecular Weight: 153.14
EC Number: 201-919-1
MDL Number: MFCD00007877
Linear Formula: H2NC6H3-2-(OH)CO2H
Product Type: Chemical
| agency | traceable to BP 1075 |
| traceable to Ph. Eur. Y0000297 | |
| traceable to USP 1392705 | |
| API family | mesalamine, mesalazine |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C7H7NO3/c8-4-1-2-6(9)5 |
| InChI key | KBOPZPXVLCULAV-UHFFFAOYSA |
| mp | 275-280 °C (dec.) (lit.) |
| Quality Level | 300  |
| SMILES string | Nc1ccc(O)c(c1)C(O)=O |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | 5-Aminosalicylic acid is a peroxidase substrate suitable for use in ELISA procedures. This substrate produces a soluble end product that is brown in color and can be read spectrophotometrically at 450 nm. The reaction may be stopped with 3 N NaOH and read at 550 nm. |
| Application: | Mesalamine may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using spectrophotometric technique. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA7173 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Mesalamine is a drug, which is structurally similar to salicylates. It exhibits anti-inflammatory activit Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | 536.0 °F |
| Flash Point(C) | 280 °C |
| mp | 275-280 °C (dec.) (lit.) |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |