Valproic acid
SIAL/PHR1061 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 2-Propylpentanoic acid; 2-Propylvaleric acid; Valproic acid
CAS Number: 99-66-1
Empirical Formula (Hill Notation): C8H16O2
Molecular Weight: 144.21
EC Number: 202-777-3
MDL Number: MFCD00002672
Linear Formula: (CH3CH2CH2)2CHCO2H
Product Type: Chemical
| agency | traceable to Ph. Eur. V0033000 |
| traceable to USP 1708707 | |
| API family | valproic acid |
| application(s) | pharmaceutical (small molecule) |
| bp | 220 °C (lit.) |
| CofA | current certificate can be downloaded |
| density | 0.9 g/mL at 25 °C (lit.) |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C8H16O2/c1-3-5-7(6-4-2 |
| InChI key | NIJJYAXOARWZEE-UHFFFAOYSA |
| Quality Level | 300  |
| refractive index | n |
| SMILES string | CCCC(C(O)=O)CCC |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Application: | Valproic acid may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations using gas chromatography technique. |
| Biochem/physiol Actions: | Anticonvulsant that also has efficacy as a mood stabilizer in bipolar disorder |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAB3712 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to pharmacopeia primary standards |
| General description: | It is widely used in the treatment of bipolar disorder, migraine, depression, epilepsy and schizophrenia. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| General description: | Valproic acid is a branched short chain fatty acid, which finds applications as a antiepileptic drug. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Recommended products: | Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H315 - H319 - H360D |
| Precautionary statements | P201 - P301 + P312 + P330 - P302 + P352 - P305 + P351 + P338 - P308 + P313 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | 231.8 °F |
| Flash Point(C) | 111 °C |
| bp | 220 °C (lit.) |
| Density | 0.9 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |