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Ethylenediaminetetraacetic acid disodium salt dihydrate

SIAL/PHR1068 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: Edetate Disodium; Edetate disodium dihydrate; Disodium ethylenediaminetetraacetate dihydrate; EDTA disodium salt; EDTA-Na2; Edathamil; Edetate disodium salt dihydrate; Sequestrene Na2

CAS Number: 6381-92-6
Empirical Formula (Hill Notation): C10H14N2Na2O8 · 2H2O
Molecular Weight: 372.24
EC Number: 205-358-3
Linear Formula: C10H14N2Na2O8 · 2H2O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-PHR1068-1G 1 g
$94.30
1/EA
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agency traceable to Ph. Eur. D2900000
  traceable to USP 1233009
API family edta
application(s) pharmaceutical (small molecule)
CofA current certificate can be downloaded
format neat
grade certified reference material
  pharmaceutical secondary standard
InChI 1S/C10H16N2O8.2Na.2H2O/c13-7(14)3-11(4-8(15)16)1-2-12(5-9(17)18)6-10(19)20;;;;/h1-6H2,(H,13,14)(H,15,16)(H,17,18)(H,19,20);;;2*1H2/q;2*+1;;/p-2
InChI key OVBJJZOQPCKUOR-UHFFFAOYSA-L
mp 248 °C (dec.) (lit.)
Quality Level 300 
SMILES string O.O.O.O.[Na+].[Na+].[Na+].[Na+].OC(=O)CN(CCN(CC([O-])=O)CC([O-])=O)CC(O)=O.OC(=O)CN(CCN(CC(O)=O)CC([O-])=O)CC([O-])=O
storage temp. 2-30°C
technique(s) gas chromatography (GC): suitable
  HPLC: suitable
Analysis Note: These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Application: Chelator of divalent cations. Inhibits enzymes, such as metalloproteases, that require divalent cations for activity.
Application: Ethylenediaminetetraacetic acid disodium salt dehydrate may be used as a reference standard in validating the potential antioxidant activity and the total phenolic content of samples of seaweed extract via metal chelation technique using ferrous ion-chelating ability assay.
Application: Ethylenediaminetetraacetic acid disodium salt dihydrate may be used as a pharmaceutical reference standard for the determination of ethylenediaminetetraacetic acid (EDTA) in pharmaceutical formulations using ion chromatography with suppressed conductimetric detection.
Application: These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Footnote: To see an example of a Certificate of Analysis for this material enter LRAA5634 in the Documents slot below. This is an example certificate only and may not be the lot that you receive.
General description: Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes: This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Recommended products: Find a digital Reference Material for this product available on our online platform ChemisTwin®  for NMR. You can use this digital equivalent on ChemisTwin®  for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here  and start your free trial .
mp 248 °C (dec.) (lit.)
Storage Temp. 2-30°C
UNSPSC 41116107

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