Phytonadione
SIAL/PHR1078 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Vitamin K1; Phytomenadione; 2-
CAS Number: 84-80-0
Empirical Formula (Hill Notation): C31H46O2
Molecular Weight: 450.70
EC Number: 201-564-2
MDL Number: MFCD00214063
Linear Formula: C31H46O2
Product Type: Chemical
| agency | traceable to BP 423 |
| traceable to Ph. Eur. P1609000 | |
| traceable to USP 1538006 | |
| API family | phytonadione |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| density | 0.984 g/mL at 25 °C (lit.) |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C31H46O2/c1-22(2)12-9- |
| InChI key | MBWXNTAXLNYFJB-NKFFZRIASA |
| mp | −20 °C (lit.) |
| Quality Level | 300  |
| refractive index | n |
| SMILES string | O=C(C1=CC=CC=C21)C(C)=C(C |
| storage condition | protect from light |
| storage temp. | 2-8°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Phytonadione may be used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAB3714 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Phytonadione belongs to the category of oral anticonvulsant drugs. It protects a newborn from acquiring hemorrhagic diseases by maintaining a normal blood clotting mechanism. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Other Notes: | Values of analytes vary lot to lot. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | −20 °C (lit.) |
| Density | 0.984 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-8°C |
| UNSPSC | 41116107 |