L-Histidine

SIAL/PHR1108 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: (S)-2-Amino-3-(4-imidazolyl)propionic acid; NSC 137773

CAS Number: 71-00-1
Empirical Formula (Hill Notation): C₆H₉N₃O₂
Molecular Weight: 155.15
EC Number: 200-745-3
MDL Number: MFCD00064315
Linear Formula: C₆H₉N₃O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-PHR1108-1G	1 g	$97.50 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	traceable to Ph. Eur. H0750000
	traceable to USP 1308505
API family	histidine
application(s)	cleaning products cosmetics flavors and fragrances food and beverages personal care pharmaceutical (small molecule)
CofA	current certificate can be downloaded
format	neat
grade	certified reference material
	pharmaceutical secondary standard
InChI	1S/C6H9N3O2/c7-5(6(10)11)1-4-2-8-3-9-4/h2-3,5H,1,7H2,(H,8,9)(H,10,11)/t5-/m0/s1
InChI key	HNDVDQJCIGZPNO-YFKPBYRVSA-N
mp	282 °C (dec.) (lit.)
Quality Level	300
SMILES string	N[C@@H](Cc1c[nH]cn1)C(O)=O
storage temp.	2-30°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Analysis Note:	These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Application:	These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions:	Precursor of histamine by action of histidine decarboxylase.
Footnote:	To see an example of a Certificate of Analysis for this material enter LRAA7159 in the slot below. This is an example certificate only and may not be the lot that you receive.
General description:	Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. L-Histidine is an essential amino acid, widely present at the active sites of enzymes. It binds to metal ions and may aid in the transport of copper. It also plays an important role for the binding of heme groups, macromolecules and phosphate groups in the binding sites of proteins.
Other Notes:	This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Recommended products:	Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial .

RIDADR	NONH for all modes of transport
WGK Germany	WGK 1
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	282 °C (dec.) (lit.)
Storage Temp.	2-30°C
UNSPSC	41116107

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