Tetracaine hydrochloride
SIAL/PHR1129 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 4-
CAS Number: 136-47-0
Empirical Formula (Hill Notation): C15H24N2O2 · HCl
Molecular Weight: 300.82
MDL Number: MFCD00038912
Linear Formula: C15H24N2O2 · HCl
Product Type: Chemical
| agency | traceable to Ph. Eur. T0500000 |
| traceable to USP 1650006 | |
| API family | tetracaine |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C15H24N2O2.ClH/c1-4-5- |
| InChI key | PPWHTZKZQNXVAE-UHFFFAOYSA |
| Quality Level | 300  |
| SMILES string | Cl.CCCCNc1ccc(cc1)C(=O)OC |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Tetracaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by high performance liquid chromatography. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Application: | Topical ophthalmic anesthetic; used for spinal anesthesia |
| Biochem/physiol Actions: | Blocks voltage-sensitive release of Ca2+ from sarcoplasmic reticulum. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA7150 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Tetracaine hydrochloride is a local anesthetic drug and an ester derivative of p-amino benzoic acid. It acts by interfering with the entry of sodium ions into nerve cells and is one of the commonly used topical anesthetics. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 - H317 - H319 |
| Precautionary statements | P280 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 25-36-43 |
| Safety Statements | 26-36/37-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |