Progesterone

SIAL/PHR1142 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: 4-Pregnene-3,20-dione

CAS Number: 57-83-0
Empirical Formula (Hill Notation): C₂₁H₃₀O₂
Molecular Weight: 314.46
EC Number: 200-350-6
MDL Number: MFCD00003658
Linear Formula: C₂₁H₃₀O₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-PHR1142-1G	1 g	$97.50 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	traceable to BP 449
	traceable to Ph. Eur. P3300000
	traceable to USP 1568007
API family	progesterone
application(s)	pharmaceutical (small molecule)
CofA	current certificate can be downloaded
format	neat
grade	certified reference material
	pharmaceutical secondary standard
InChI	1S/C21H30O2/c1-13(22)17-6-7-18-16-5-4-14-12-15(23)8-10-20(14,2)19(16)9-11-21(17,18)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18-,19-,20-,21+/m0/s1
InChI key	RJKFOVLPORLFTN-LEKSSAKUSA-N
mp	128-132 °C (lit.)
Quality Level	300
SMILES string	CC(=O)[C@H]1CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3CC[C@]12C
storage temp.	2-30°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Analysis Note:	These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Application:	Progesterone may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceuticals and environmental samples by liquid chromatography (LC) and gas chromatography/mass spectrometry (GC/MS), liquid chromatography/mass spectrometry (LC/MS) and liquid chromatography/tandem mass spectrometry (LC/MS/MS), respectively.
Application:	These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Biochem/physiol Actions:	Induces maturation and secretory activity of the uterine endothelium; suppresses ovulation. Progesterone is implicated in the etiology of breast cancer.
Footnote:	To see an example of a Certificate of Analysis for this material enter LRAA7142 in the slot below. This is an example certificate only and may not be the lot that you receive.
General description:	Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards.
Other Notes:	Steroid hormone produced by the corpus luteum.
Other Notes:	This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Other Notes:	Values of analytes vary lot to lot.

Symbol	GHS08
Signal word	Danger
Hazard statements	H351 - H360FD - H362
Precautionary statements	P202 - P260 - P263 - P264 - P270 - P308 + P313
Hazard Codes	Xn
Risk Statements	40-62
Safety Statements	36/37
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3

mp	128-132 °C (lit.)
Storage Temp.	2-30°C
UNSPSC	41116107

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