Lisinopril
SIAL/PHR1143 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: (S)
CAS Number: 83915-83-7
Empirical Formula (Hill Notation): C21H31O5N3 · 2H2O
Molecular Weight: 441.52
MDL Number: MFCD01698825
Linear Formula: C21H31O5N3 · 2H2O
Product Type: Chemical
| agency | traceable to BP 695 |
| traceable to Ph. Eur. L0702000 | |
| traceable to USP 1368609 | |
| API family | lisinopril |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C21H31N3O5.2H2O/c22-13 |
| InChI key | CZRQXSDBMCMPNJ-ZUIPZQNBSA |
| Quality Level | 300  |
| SMILES string | [H]O[H].[H]O[H].NCCCC[C@H |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Lisinopril may be used as a pharmaceutical reference standard for the quantification of the analyte in pharmaceutical formulations using kinetic spectrophotometric technique. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Biochem/physiol Actions: | Angiotensin converting enzyme (ACE) inhibitor. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAB3302 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Lisinopril is a lysine derivative of enalaprilat and belongs to the group of angiotensin converting enzyme (ACE) inhibitors. It is widely used as an orally active medication in the treatment of high blood pressure and may be used to treat congestive heart failure. |
| General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Other Notes: | Values of analytes vary lot to lot. |
| Symbol |  GHS08 |
| Signal word | Danger |
| Hazard statements | H360D - H373 |
| Precautionary statements | P202 - P260 - P280 - P308 + P313 - P405 - P501 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |