Phenyl salicylate melting point standard
SIAL/PHR1152 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Phenyl salicylate; Salol
CAS Number: 118-55-8
Empirical Formula (Hill Notation): C13H10O3
Molecular Weight: 214.22
EC Number: 204-259-2
MDL Number: MFCD00002213
Linear Formula: 2-(HO)C6H4CO2C6H5
Product Type: Chemical
| agency | traceable to USP 1534209 |
| API family | phenyl salicylate |
| application(s) | pharmaceutical (small molecule) |
| bp | 172-173 °C/12 mmHg (lit.) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C13H10O3/c14-12-9-5-4- |
| InChI key | ZQBAKBUEJOMQEX-UHFFFAOYSA |
| mp | 41-43 °C (lit.) |
| ~Approximately 42 °C | |
| Quality Level | 300  |
| SMILES string | Oc1ccccc1C(=O)Oc2ccccc2 |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Phenyl salicylate may be used as an analytical reference standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA7176 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Phenyl salicylate is a phenyl ester of salicylic acid and is used as a medicine under the name ′salol′ as an internal antiseptic. It finds its application in paints, waxes, and varnishes as it is found to absorb UV radiation in the range of 290-325 nm. It also shows its presence in cosmetics and sunscreens as a UV filter. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Other Notes: | Values of analytes vary lot to lot. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 2 |
| Flash Point(F) | 235.4 °F - closed cup |
| Flash Point(C) | 113 °C - closed cup |
| bp | 172-173 °C/12 mmHg (lit.) |
| mp | ~Approximately 42 °C; 41-43 °C (lit.) |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |