Triethyl citrate
SIAL/PHR1153 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Ethyl citrate
CAS Number: 77-93-0
Empirical Formula (Hill Notation): C12H20O7
Molecular Weight: 276.28
EC Number: 201-070-7
MDL Number: MFCD00009201
Linear Formula: HOC(COOC2H5)(CH2COOC2H5)2
Product Type: Chemical
| agency | traceable to USP 1683606 |
| API family | triethyl citrate |
| application(s) | pharmaceutical (small molecule) |
| bp | 235 °C/150 mmHg (lit.) |
| CofA | current certificate can be downloaded |
| density | 1.14 g/mL at 25 °C (lit.) |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| greener alternative category | Aligned  |
| greener alternative product characteristics | Less Hazardous Chemical Syntheses Learn more about the Principles of Green Chemistry . |
| InChI | 1S/C12H20O7/c1-4-17-9(13) |
| InChI key | DOOTYTYQINUNNV-UHFFFAOYSA |
| Quality Level | 300 |
| refractive index | n |
| SMILES string | CCOC(=O)CC(O)(CC(=O)OCC)C |
| storage temp. | 2-30°C |
| sustainability | Greener Alternative Product |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor density | 9.7 (vs air) |
| vapor pressure | 1 mmHg ( 107 °C) |
| Analysis Note: | These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Application: | Triethyl citrate can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography. |
| General description: | Triethyl citrate is an ester of citric acid and is commonly used as a plasticizer in pharmaceutical coatings including tablets, capsules, beads and granules for masking taste. It is also used as a flavoring agent in food. Certified pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to in-house working standards. |
| General description: | We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product can replace highly toxic diluents in membrane preparation and thus aligns with "Less Hazardous Chemical Syntheses". Click here  for more information. |
| Other Notes: | Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Other Notes: | To see an example of a Certificate of Analysis for this material enter LRAA8988 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| Other Notes: | Values of analytes vary lot to lot. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 311.0 °F - closed cup |
| Flash Point(C) | 155 °C - closed cup |
| bp | 235 °C/150 mmHg (lit.) |
| Density | 1.14 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |