Tributyl 2-acetylcitrate
SIAL/PHR1156 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: Acetyl tributyl citrate
CAS Number: 77-90-7
Empirical Formula (Hill Notation): C20H34O8
Molecular Weight: 402.48
EC Number: 201-067-0
MDL Number: MFCD00043554
Linear Formula: CH3CO2C[CO2(CH2)3CH3][CH2CO2(CH2)3CH3]2
Product Type: Chemical
| agency | traceable to Ph. Eur. Y0001055 |
| traceable to USP 1009901 | |
| API family | acetyltributyl citrate |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| density | 1.05 g/mL at 25 °C (lit.) |
| description | API family: acetyltributyl citrate |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| greener alternative category | Aligned  |
| greener alternative product characteristics | Less Hazardous Chemical Syntheses Learn more about the Principles of Green Chemistry . |
| InChI | 1S/C20H34O8/c1-5-8-11-25- |
| InChI key | QZCLKYGREBVARF-UHFFFAOYSA |
| Quality Level | 300 |
| refractive index | n |
| SMILES string | CCCCOC(=O)CC(CC(=O)OCCCC) |
| storage temp. | 2-30°C |
| sustainability | Greener Alternative Product |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor pressure | 0.26 psi ( 20 °C) |
| 0.8 psi ( 55 °C) |
| Analysis Note: | These secondary standards offer multi-traceability to the USP and EP (PhEur) primary standards, where they are available. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Application: | Tributyl 2-acetylcitrate may be used as a pharmaceutical reference standard for the determination of the analyte in bulk drug and pharmaceutical formulations by gas chromatography. |
| General description: | Tributyl 2-acetylcitrate is a hydrophobic biodegradable plasticizer, that is usually synthesized by esterification of citric acid. Pharmaceutically, it is used as an excipient, which is generally applied as a thin film over the tablets or capsules. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| General description: | We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Green Chemistry. This product is environmentally-benign and can replace highly toxic phthalates in membrane preparation and thus aligns with "Less Hazardous Chemical Syntheses". Click here  for more information. |
| Other Notes: | Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Other Notes: | To see an example of a Certificate of Analysis for this material enter LRAA8991 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| Other Notes: | Values of analytes vary lot to lot. |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | 422.6 °F - closed cup |
| Flash Point(C) | 217 °C - closed cup |
| Density | 1.05 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |