Procaine hydrochloride
SIAL/PHR1161 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 4-Aminobenzoic acid 2-diethylaminoethyl ester; p-Aminobenzoic acid diethylaminoethyl ester hydrochloride; Novocaine hydrochloride
CAS Number: 51-05-8
Empirical Formula (Hill Notation): C13H20N2O2 · HCl
Molecular Weight: 272.77
EC Number: 200-077-2
MDL Number: MFCD00013000
Linear Formula: H2NC6H4CO2CH2CH2N(C2H5)2·HCl
Product Type: Chemical
| agency | traceable to USP 1564006 |
| API family | procaine |
| application(s) | pharmaceutical (small molecule) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C13H20N2O2.ClH/c1-3-15 |
| InChI key | HCBIBCJNVBAKAB-UHFFFAOYSA |
| mp | 155-156 °C (lit.) |
| Quality Level | 300  |
| SMILES string | Cl.CCN(CC)CCOC(=O)c1ccc(N |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Procaine hydrochloride can be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by electrochemical, chemiluminescence, and spectrophotometric techniques. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA7177 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Procaine hydrochloride is a synthetic compound that belongs to the class of local anesthetic drugs. It has a structure similar to the natural compounds that participate in nerve impulse transmission. It shows interaction with the cellular membranes causing membrane lipids to expand, membrane-bound calcium to displace and change the structure of the proteins that are responsible for regulating the cell permeability and shape. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Other Notes: | Values of analytes vary lot to lot. |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 |
| Precautionary statements | P301 + P310 + P330 |
| Hazard Codes | T |
| Risk Statements | 25-43 |
| Safety Statements | 36/37/39-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| mp | 155-156 °C (lit.) |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |