Loperamide hydrochloride

SIAL/PHR1162 - Pharmaceutical Secondary Standard; Certified Reference Material

Synonym: LPM; 4-(p-Chlorophenyl)-4-hydroxy-N,N-dimethyl-α,α-diphenyl-1-piperidinebutyramide hydrochloride

CAS Number: 34552-83-5
Empirical Formula (Hill Notation): C₂₉H₃₃ClN₂O₂ · HCl
Molecular Weight: 513.50
EC Number: 252-082-4
MDL Number: MFCD00058581
Linear Formula: C₂₉H₃₃ClN₂O₂ · HCl
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-PHR1162-1G	1 g	$107.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

agency	traceable to BP 635
	traceable to Ph. Eur. L0750000
	traceable to USP 1370000
API family	loperamide
application(s)	pharmaceutical (small molecule)
CofA	current certificate can be downloaded
format	neat
grade	certified reference material
	pharmaceutical secondary standard
InChI	1S/C29H33ClN2O2.ClH/c1-31(2)27(33)29(24-9-5-3-6-10-24,25-11-7-4-8-12-25)19-22-32-20-17-28(34,18-21-32)23-13-15-26(30)16-14-23;/h3-16,34H,17-22H2,1-2H3;1H
InChI key	PGYPOBZJRVSMDS-UHFFFAOYSA-N
Quality Level	300
SMILES string	Cl.CN(C)C(=O)C(CCN1CCC(O)(CC1)c2ccc(Cl)cc2)(c3ccccc3)c4ccccc4
storage temp.	2-30°C
technique(s)	gas chromatography (GC): suitable
	HPLC: suitable

Analysis Note:	These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available.
Application:	Loperamide hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by spectrophotometric and chromatography techniques.
Application:	These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements.
Footnote:	To see an example of a Certificate of Analysis for this material enter LRAC3771 in the slot below. This is an example certificate only and may not be the lot that you receive.
General description:	Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Loperamide hydrochloride finds application in the regulation and symptomatic relief of long acting diarrhea linked with inflammatory bowel diseases. It can also be used as a muscle relaxant agent.
Other Notes:	This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis.
Other Notes:	Values of analytes vary lot to lot.

Symbol	GHS06
Signal word	Danger
Hazard statements	H301
Precautionary statements	P301 + P310
Hazard Codes	T
Risk Statements	25
Safety Statements	45
RIDADR	UN 2811 6.1 / PGIII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Storage Temp.	2-30°C
UNSPSC	41116107

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