Imidazole
SIAL/PHR1180 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 1,3-
CAS Number: 288-32-4
Empirical Formula (Hill Notation): C3H4N2
Molecular Weight: 68.08
EC Number: 206-019-2
MDL Number: MFCD00005183
Linear Formula: C3H4N2
Product Type: Chemical
| agency | traceable to Ph. Eur. I0086000 |
| traceable to USP 1336500 | |
| API family | imidazole |
| application(s) | pharmaceutical (small molecule) |
| bp | 256 °C (lit.) |
| CofA | current certificate can be downloaded |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C3H4N2/c1-2-5-3-4-1/h1 |
| InChI key | RAXXELZNTBOGNW-UHFFFAOYSA |
| mp | 88-91 °C (lit.) |
| pKa (25 °C) | 6.95 |
| Quality Level | 300  |
| SMILES string | c1c[nH]cn1 |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor pressure | <1 mmHg ( 20 °C) |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
| Application: | Excellent for buffers in the range of pH 6.2-7.8 |
| Application: | Imidazole may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by high performance liquid chromatography (HPLC). |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC4011 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Symbol |    GHS05,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H314 - H360D |
| Precautionary statements | P201 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 61-22-34 |
| Safety Statements | 53-26-36/37/39-45 |
| RIDADR | UN 3263 8 / PGIII |
| WGK Germany | WGK 2 |
| Flash Point(F) | 293.0 °F - closed cup |
| Flash Point(C) | 145 °C - closed cup |
| bp | 256 °C (lit.) |
| mp | 88-91 °C (lit.) |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |