Papaverine hydrochloride
SIAL/PHR1182 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 6,7-
CAS Number: 61-25-6
Empirical Formula (Hill Notation): C20H21NO4 · HCl
Molecular Weight: 375.85
EC Number: 200-502-1
MDL Number: MFCD00012745
Linear Formula: C20H21NO4 · HCl
Product Type: Chemical
agency | traceable to BP 277 |
traceable to Ph. Eur. P0270000 | |
traceable to USP 1496008 | |
application(s) | food and beverages pharmaceutical (small molecule) |
CofA | current certificate can be downloaded |
format | neat |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C20H21NO4.ClH/c1-22-17 |
InChI key | UOTMYNBWXDUBNX-UHFFFAOYSA |
Quality Level | 300 ![]() |
SMILES string | COC1=C(OC)C=C(C(CC2=CC(OC |
storage temp. | 2-30°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
Application: | Papaverine hydrochloride is used as a pharmaceutical reference standard in the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques. |
Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
Biochem/physiol Actions: | Smooth muscle relaxant and cerebral vasodilator; phosphodiesterase inhibitor. |
Footnote: | To see an example of a Certificate of Analysis for this material enter LRAA9001 in the slot below. This is an example certificate only and may not be the lot that you receive. |
General description: | Papaverine hydrochloride is the hydrochloride salt of an opiate derivative called papaverine, a benzylisoquinoline compound. It has been found to relax smooth muscles of blood vessels and is used in the management of occlusivity and spasticity of pulmonary, coronary and peripheral arteries. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol | ![]() |
Signal word | Danger |
Hazard statements | H301 |
Precautionary statements | P264 - P270 - P301 + P310 - P405 - P501 |
Hazard Codes | Xn |
Risk Statements | 22 |
Safety Statements | 22 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 1 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Storage Temp. | 2-30°C |
UNSPSC | 41116107 |