Methyl Ethyl Ketone
SIAL/PHR1207 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 2-Butanone; Ethyl methyl ketone; MEK; Methyl ethyl ketone
CAS Number: 78-93-3
Empirical Formula (Hill Notation): C4H8O
Molecular Weight: 72.11
EC Number: 201-159-0
MDL Number: MFCD00011648
Linear Formula: C2H5COCH3
Product Type: Chemical
| agency | traceable to USP 1430101 |
| application(s) | pharmaceutical (small molecule) |
| autoignition temp. | 960 °F |
| bp | 80 °C (lit.) |
| CofA | current certificate can be downloaded |
| density | 0.805 g/mL at 25 °C (lit.) |
| expl. lim. | 10.1 % |
| format | neat |
| grade | certified reference material |
| pharmaceutical secondary standard | |
| InChI | 1S/C4H8O/c1-3-4(2)5/h3H2, |
| InChI key | ZWEHNKRNPOVVGH-UHFFFAOYSA |
| mp | −87 °C (lit.) |
| Quality Level | 300  |
| refractive index | n |
| SMILES string | CC(CC)=O |
| storage temp. | 2-30°C |
| technique(s) | gas chromatography (GC): suitable |
| HPLC: suitable | |
| vapor density | 2.49 (vs air) |
| vapor pressure | 71 mmHg ( 20 °C) |
| Analysis Note: | These secondary standards offer multi-traceability to the USP, EP and BP primary standards, where they are available. |
| Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
| Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC0146 in the slot below. This is an example certificate only and may not be the lot that you receive. |
| General description: | Pharmaceutical secondary standards for application in quality control provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. 2-Butanone (Methyl ethyl ketone, MEK), an aliphatic ketone, is considered as an aprotic and protophilic solvent. Its ability as an anticonvulsive agent in lithium-pilocarpine-induc |
| Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
| Recommended products: | Find a digital Reference Material for this product available on our online platform ChemisTwin® for NMR. You can use this digital equivalent on ChemisTwin® for your sample identity confirmation and compound quantification (with digital external standard). An NMR spectrum of this substance can be viewed and an online comparison against your sample can be performed with a few mouseclicks. Learn more here and start your free trial . |
| Symbol |   GHS02,GHS07 |
| Signal word | Danger |
| Hazard statements | H225 - H319 - H336 |
| Precautionary statements | P210 - P305 + P351 + P338 |
| Hazard Codes | F,Xi |
| Risk Statements | 11-36-66-67 |
| Safety Statements | 9-16 |
| RIDADR | UN1193 - class 3 - PG 2 - Ethyl methyl ketone |
| WGK Germany | WGK 1 |
| Flash Point(F) | 26.6 °F - closed cup |
| Flash Point(C) | -3 °C - closed cup |
| Supplemental Hazard Statements | EUH066 |
| bp | 80 °C (lit.) |
| mp | −87 °C (lit.) |
| Density | 0.805 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | 2-30°C |
| UNSPSC | 41116107 |