trans-Anethole
SIAL/PHR1218 - Pharmaceutical Secondary Standard; Certified Reference Material
Synonym: 4-Propenylanisole; trans-
CAS Number: 4180-23-8
Empirical Formula (Hill Notation): C10H12O
Molecular Weight: 148.20
EC Number: 224-052-0
MDL Number: MFCD00009284
Linear Formula: CH3CH=CHC6H4OCH3
Product Type: Chemical
agency | traceable to USP 1035005 |
application(s) | pharmaceutical (small molecule) |
bp | 234-237 °C (lit.) |
CofA | current certificate can be downloaded |
density | 0.988 g/mL at 25 °C (lit.) |
format | neat |
grade | certified reference material |
pharmaceutical secondary standard | |
InChI | 1S/C10H12O/c1-3-4-9-5-7-1 |
InChI key | RUVINXPYWBROJD-ONEGZZNKSA |
mp | 20-21 °C (lit.) |
Quality Level | 300 ![]() |
refractive index | n |
SMILES string | COc1ccc(C=CC)cc1 |
storage temp. | 2-30°C |
technique(s) | gas chromatography (GC): suitable |
HPLC: suitable |
Analysis Note: | These secondary standards offer multi-traceability to the USP, EP (PhEur) and BP primary standards, where they are available. |
Application: | trans-Anethole may be used as an analytical reference standard for the determination of the analyte in raw material, food products and pharmaceutical formulations by high performance liquid chromatography and gas chromatography. |
Application: | These Secondary Standards are qualified as Certified Reference Materials. These are suitable for use in several analytical applications including but not limited to pharma release testing, pharma method development for qualitative and quantitative analyses, food and beverage quality control testing, and other calibration requirements. |
Biochem/physiol Actions: | Naturally occurring phenylpropene derivative that is estrogenic at lower concentrations and cytotoxic at higher concentrations to cancer cell lines. The cytotoxicity is related to the metabolism of trans-anethole to 4-hydroxy-1-propenylbenze |
Footnote: | To see an example of a Certificate of Analysis for this material enter LRAC3326 in the slot below. This is an example certificate only and may not be the lot that you receive. |
General description: | trans-Anethole is an aromatic monoterpenoid compound and derivative of phenylpropene. It is predominantly used as a fragrance in cosmetics and as a flavoring agent in food and pharmaceutical industries. Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. |
Other Notes: | This Certified Reference Material (CRM) is produced and certified in accordance with ISO 17034 and ISO/IEC 17025. All information regarding the use of this CRM can be found on the certificate of analysis. |
Symbol | ![]() ![]() |
Signal word | Warning |
Hazard statements | H317 - H411 |
Precautionary statements | P261 - P272 - P273 - P280 - P302 + P352 - P333 + P313 |
Hazard Codes | Xi,N |
Risk Statements | 43-51/53 |
Safety Statements | 36/37-61 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 2 |
Flash Point(F) | 213.8 °F |
Flash Point(C) | 101 °C |
bp | 234-237 °C (lit.) |
mp | 20-21 °C (lit.) |
Density | 0.988 g/mL at 25 °C (lit.) |
Refractive Index | n |
Storage Temp. | 2-30°C |
UNSPSC | 41116107 |